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wound care clinic

Wound Care Treatments in Jeffersonville, IN and Louisville – Local Clinic

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If you have a wound that is not closing, a sore that keeps reopening, or an ulcer that is starting to worry you, you are not alone. Chronic wounds are more common than most people realize, especially for patients dealing with diabetes, poor circulation, neuropathy, mobility limits, or recovery after surgery. The frustrating part is that many people get stuck in a loop: a quick dressing change, a quick “keep it clean,” then back again next week with the same wound that looks almost identical. Our Jeffersonville, Indiana wound care clinic (minutes from Louisville) is built to break that cycle. We provide full-service wound care for patients with Medicare and we also work with many private insurance plans. We start with the standard of care that wound patients should receive, consistently and correctly. But we do not stop there. If your wound is not resolving, our protocol shifts into a higher gear: deeper evaluation to identify why the wound is stalled, and more advanced treatment options designed to help you heal and stay healed.

  • Chronic wounds often fail to heal because the underlying cause (circulation, swelling, pressure, infection, nutrition, glucose control) is not being addressed, not because you “need more time.”

  • We provide standard wound care first, but if you are not progressing, we escalate to advanced options and deeper evaluation with the goal of full resolution.

  • Medicare commonly covers outpatient wound care-related services and may cover home health wound care for eligible patients; certain therapies (like hyperbaric oxygen) have specific coverage rules.

  • Many private insurers cover advanced therapies when criteria are met, and published policies often outline what documentation is required.

  • The goal is not endless visits. The goal is healing, reducing recurrence, and getting you back to normal life.

Our goal is simple: resolve the condition so you are not coming back again and again for basic wound care.

Who we help

We treat both acute and chronic wounds, including:

  • Diabetic foot ulcers and toe wounds

  • Venous leg ulcers (often associated with swelling and varicose veins)

  • Pressure injuries (bed sores)

  • Surgical wounds that are slow to close

  • Traumatic wounds, lacerations, or crush injuries that are not progressing

  • Infected wounds (including wounds with cellulitis or high drainage)

  • Wounds complicated by poor circulation, neuropathy, or repeated pressure

If you have been told “it just takes time,” but it has been weeks (or months) with little progress, it is worth getting a wound-specific evaluation.

What “full wound care services” really means

Good wound care is not one treatment. It is a coordinated plan that addresses the wound itself and the reasons it is not healing. Depending on your needs, your care plan may include:

  • Comprehensive wound assessment and measurements
    We document size, depth, tissue quality, drainage, odor, signs of infection, and progress over time. This matters for outcomes, but it also matters for coverage and medical necessity documentation.
  • Debridement (when appropriate)
    Removing non-viable tissue can be a turning point for healing, because it reduces bioburden and allows healthy tissue to grow.
  • Infection management
    That can include topical antimicrobials, culture guidance, or coordination for systemic antibiotics when needed.
  • Advanced dressings and moisture balance
    Wounds can stall when they are too wet, too dry, or repeatedly traumatized by poor dressing choice. Dressings are not “one size fits all,” and we adjust based on drainage, tissue type, and healing stage.
  • Compression therapy for venous ulcers and swelling
    Leg ulcers often fail to heal when swelling is not controlled. Compression is frequently a core part of treatment.
  • Offloading and pressure reduction
    For foot ulcers, what you do between visits matters. Pressure and friction can erase progress. Offloading strategies reduce stress on the wound so tissue can actually rebuild.
  • Negative Pressure Wound Therapy (NPWT)
    For certain wounds, NPWT can help remove excess fluid and support healthy granulation, improving the wound environment. (Many insurers have specific criteria for coverage, so we document carefully.)
  • Skin substitutes or tissue-based products when medically appropriate
    These products are typically considered only after a period of standard wound care has been attempted and documented, and when the wound still has not progressed. Coverage rules vary by insurer.
  • Care coordination when circulation or biomechanics are the issue
    Some wounds will not close until blood flow is addressed, pressure points are corrected, or glucose control and nutrition are improved. We coordinate with the right specialties when needed.
  • Medicare-covered supportive services when applicable
    For example, Medicare Part B may cover certain surgical dressing services depending on the wound and setting.
    Medicare may also cover home health services that include skilled nursing wound care for eligible patients.

Our care philosophy: standard of care first, then deeper solutions if you are not healing

A lot of “wound care” out in the wild is basically maintenance: clean it, cover it, repeat. That can be appropriate early on. But if a wound is stalled, repeating the same basics without changing the plan is how people end up with months of appointments and a wound that never truly resolves. Our protocol starts with standard wound care because it works for many patients when done correctly and consistently. Medicare and many insurers also expect this foundation before they will consider some advanced therapies. For example, in hyperbaric oxygen therapy guidance, coverage is described as adjunctive and tied to specific conditions and documentation of response to standard wound care.

If your wound is not improving on a reasonable timeline, we step back and ask the questions that change outcomes:

  • Is there a circulation issue that needs to be addressed?

  • Is swelling sabotaging healing?

  • Is pressure or gait mechanics repeatedly reopening the tissue?

  • Is infection or biofilm keeping the wound inflamed?

  • Is nutrition, glucose control, or another underlying factor blocking repair?

When the “why” is identified, the “what” becomes clearer. That is where advanced strategies come in.

Advanced care when healing is not happening

If the wound is not resolving, we may consider more advanced options based on your condition, risk factors, and coverage guidelines. This can include:

  • Escalation to advanced dressings or devices (such as NPWT)

  • Skin substitutes or other advanced wound products when criteria are met

  • Additional diagnostics or referrals to address vascular problems, uncontrolled edema, or structural foot issues

  • A more “root-cause” approach to reduce recurrence risk once the wound closes

And when appropriate and clinically indicated, we also offer more advanced solutions, including regenerative-focused treatments, aimed at improving tissue healing capacity and targeting the underlying reason the wound formed in the first place. The intent is not to keep layering services forever. The intent is to help you heal and stay healed.

Medicare and insurance coverage for wound care: what patients should know

Most patients do not need to become insurance experts, but a little clarity helps you plan.

Medicare Part B (Medical Insurance) commonly applies to outpatient wound care services, physician services, and certain covered therapies in eligible settings. For example:

  • Medicare covers surgical dressing services in appropriate situations and settings.

  • Medicare may cover home health services including skilled nursing wound care for eligible patients.

  • Medicare Part B may cover hyperbaric oxygen therapy for specific covered conditions, under defined criteria.

  • For patients with diabetes who meet criteria, Medicare may cover therapeutic shoes and inserts to reduce foot injury risk and recurrence.

Private insurance plans often cover standard wound care and may cover advanced therapies (NPWT, certain skin substitutes, etc.) when medical necessity criteria are met. Policies vary and can change. Here are examples of insurer policy resources that commonly outline criteria for advanced wound products and therapies.

Coverage resources (official pages)

These links are for patient education and general plan reference. Coverage depends on your specific plan and medical necessity.

Medicare: Surgical dressing services
https://www.medicare.gov/coverage/surgical-dressing-services

Medicare: Home health services (includes skilled nursing wound care when eligible)
https://www.medicare.gov/coverage/home-health-services

Medicare: Hyperbaric oxygen therapy
https://www.medicare.gov/coverage/hyperbaric-oxygen-therapy

Medicare: Therapeutic shoes & inserts for diabetes
https://www.medicare.gov/coverage/therapeutic-shoes-inserts

Aetna: Skin and soft tissue substitutes (clinical policy)
https://www.aetna.com/cpb/medical/data/200_299/0244.html

Cigna: Tissue engineered skin substitutes (coverage policy PDF)
https://static.cigna.com/assets/chcp/pdf/coveragePolicies/medical/mm_0068_coveragepositioncriteria_woundhealing.pdf

UnitedHealthcare: Negative pressure wound therapy (medical policy PDF)
https://www.uhcprovider.com/content/dam/provider/docs/public/policies/comm-medical-drug/negative-pressure-wound-therapy.pdf


When to book a wound care consultation

If you are on the fence, here are signs it is time to get seen:

  • The wound has not significantly improved in 2 to 4 weeks

  • You have diabetes and any foot wound, even if it “looks small”

  • The wound is painful, foul-smelling, increasingly red, or draining more

  • You keep getting the same wound in the same spot

  • You have swelling in the legs that is not being managed

  • You were recently hospitalized or had surgery and the wound is slow to close

Call to action: let’s get a plan in place

If you are in Jeffersonville, IN or the Louisville area and dealing with a wound that is not healing, schedule a consultation. We will evaluate the wound, explain what is happening in plain language, and map out a step-by-step plan.

CTA options you can use on the page:

  • Book a wound care consultation today (Medicare accepted)

  • Call to schedule an evaluation for chronic ulcers, diabetic wounds, or post-surgical wounds

  • Request an appointment and bring your insurance card and medication list

  • Get a second opinion if you have been stuck in “maintenance mode”

 

 

FAQ

1) Do you accept Medicare for wound care visits?

Yes. We treat Medicare patients and provide the documentation typically required for covered wound care services. Medicare also publishes patient-facing coverage pages for related services like surgical dressing services and home health services.

2) What should I bring to my first appointment?

Bring your insurance card(s), photo ID, a medication list, recent discharge papers if you were hospitalized, and any wound care supplies you have been using. If you have photos showing how the wound changed over time, those can help too.

3) How long does it take for a chronic wound to heal?

There is no universal timeline. Healing depends on circulation, infection status, pressure, swelling, diabetes control, nutrition, and the type of wound. The key is that we should see measurable progress with an appropriate plan. If you are not progressing, the plan needs to change.

4) Do you treat diabetic foot ulcers?

Yes. Diabetic foot wounds are a major focus because they can worsen quickly without proper offloading, infection control, and consistent wound management. Medicare also has coverage guidance for therapeutic shoes and inserts for eligible diabetic patients to reduce injury risk.

5) Will insurance cover advanced wound treatments like NPWT or skin substitutes?

Often, yes, when medical necessity criteria are met. Many insurers publish medical policies outlining when therapies like NPWT or skin substitutes are covered. We help document your course of care appropriately.

6) Do you offer hyperbaric oxygen therapy?

If hyperbaric oxygen therapy is appropriate, we can discuss it and coordinate care pathways. Medicare Part B covers hyperbaric oxygen therapy for specific conditions and situations, with defined eligibility criteria.

7) What makes your clinic different from “basic wound care”?

We do not want you stuck in repeat dressing changes with the same non-healing wound. We start with standard of care, but if the wound is not resolving, we move into a more advanced, problem-solving approach that targets why the wound is stalled and how to prevent recurrence. The goal is closure, stability, and fewer return visits over time.

stroke rehabilitation louisville

What “Better Blood Flow” Can Mean for Stroke Rehabilitation in Louisville, Kentuckiana: Walking Distance, Hands, and Focus

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stroke rehabilitation in louisville

Regenerative Medicine by Dr. Rafael F. Cruz MD who has practiced medicine for 30+ years and is a physician educator researcher and inventor of Cruz Cric.

Dr. Rafael F. Cruz MD board-certified in Emergency Medicine twice and has practiced for about 10 years. He received 2 years of anesthesia training at the University of Louisville, with an emphasis on procedures that relieve pain. His career then shifted to Integrative, functional, and regenerative medicine, focusing on helping patients improve their health, manage complicated conditions, and reduce the risk of both acute and chronic diseases.

Dr. Cruz is a fellow and founding member of the American Academy of Ozone Therapists. He also received training in IV Vitamin Therapy, IV Chelation and IV Chelation from ACAM (the American College for the Advancement in Medicine). Dr. Cruz also trained at the Riordan Clinic in Wichita, Kansas, which focuses on complementary approaches to care, including IV vitamin C and IV Ozone, used to support cancer patients and those with chronic immune dysfunction like autoimmune Lyme syndrome.

Dr. Cruz, a clinician by profession, is also an educator, a medical writer, a lifelong student and inventor of the “cruzcric”, a pocket-sized emergency surgical airway tool.

Dr. Cruz is the founder and director of Kentuckiana Integrative Medicine, a clinic that combines the best of modern conventional medicine with natural integrative therapies. He is known for his thorough and detailed evaluations. He works collaboratively with primary and specialist care providers. When needed, Dr. Cruz uses image-guided ultrasound and or fluoroscopy to improve injection accuracy for soft-tissue and musculoskeletal conditions, including tendon and rotator cuff tears, and arthritic joint and spinal conditions. The clinic also supports patients with more complicated needs such as neurological [Stroke, Brain injury, Parkinsons, MS, CRPS], Mental Health Addiction [Ketamine Therapy], cardiovascular issues, hormonal optimization, sexual health, sexual dysfunction, stress urinary incontinence and medical weight loss.

Kentuckiana Integrative Medicine has been serving Louisville and the greater Kentuckiana area for over 20 years, providing compassionate care and individualized therapy plans.

Stroke recovery requires more than just a few weeks’ effort. Stroke recovery requires a steady effort of PT and OT, as well as daily home practice. It also takes mental endurance to remain engaged even when progress is slow. We see it every day at Kentuckiana Integrative Medicine with our stroke rehabilitation in Louisville patients. Our approach to recovery is based on a clinical question: What internal factors help the brain and body respond, and what factors might be quietly limiting progress?

We consider brain blood flow and removal of brain inflammation as some of the most critical factors. Many patients report neurological improvements in their daily lives when inflammation is reduced and blood flow is improved. Patients describe feeling lighter, a hand responding more consistently, improved thinking, steady balance, better walking and increased strength and stamina. These are not abstract goals. They’re functional markers that influence independence, self-confidence, and daily quality of life.

Repetition and recovery are the foundations of rehabilitation gains. The nervous system can run out of energy, muscles can fatigue, or cognitive stamina can be low. This can lead to fewer quality repetitions and stalling of progress, even when a person is exerting strong effort. The brain and body can tolerate more activity, recover more quickly between sessions and get more out of every therapy session or home exercise routine when brain inflammation is reduced and vascular system function is improved.

Our approach is integrated. Stroke recovery is not viewed as a neurologic or muscular issue. We structure our care to support the bigger picture of improved neuromuscular function, such as walking distance, arm and leg function, focus and concentration. These impairments often improve when the brain and vascular system are moved in the right directions.

REGRETABLY INSURANCE CANNOT BE ACCEPTED as these therapies are NOT FDA approved, NOT covered by insurance who considers these therapies “experimental” in nature despite the wonderful evidence of tremendous benefits.

Consultations are $400 paid in advance, but FREE and credited back to you if you invest $6,500+ in your health.

We do NOT sell your information like your Name, email and phone number.

We will NOT call you to schedule an appointment.

PLEASE CALL OUR OFFICE 812-913-4416.

You will need to call our office to schedule your appointment for an in person visit or from your home via Telemedicine Phone/Zoom. Your choice.

For a limited time, get $100 off your consultation fee with code “NRC2025.” Contact us today on 812-913-4416 or learn more at www.regenmedky.com.

How Blood Flow Affects Stroke Recovery

A stroke is an event that is usually caused by reduced blood flow to the brain, leading to brain inflammation, some brain cell death and reduced brain blood flow. Many people, after the emergency phase, focus on what they can feel and see: weakness, spasticity or balance problems, changes in speech, numbness or pain, mood swings, or brain fog.

The patient’s recovery may be affected by the small and large blood vessels that have experienced blockage, resulting in brain inflammation and damage. If the vascular system is stressed (plaque buildup, impaired circulation, inflammation, endothelial dysfunction), then the brain and other peripheral tissues may not receive optimal oxygen and nutrients. This can show up as:

  • Exercise tolerance reduced
  • Recovery after physical activity is slower
  • Cold extremities and poor peripheral circulation
  • Cognitive fatigue and brain fog
  • Unexplainable “Plateaus”

Dr. Rafael F. Cruz MD discusses Regenerative Injection Therapies; 1] Personal High Dose Hyper-concentrated Photo-energized Platelet Rich Plasma and 2] Regenerative Personal Human Harvested Messenger Signaling “Stem” Cellular Injection Therapy.

Mary Lindel 85% Heart Artery blockage, Carotid Artery Blockage with Shortness of breath, Fatigue and Ankle swelling advised to have Bypass Heart Surgery by 2 Heart surgeons. 

What “Better Blood Flow” Can Look Like in Daily Life

Stroke survivors seldom describe their recovery as a lab number; instead, they describe it by functional tasks, such as walking through the grocery store, carrying bags, buttoning shirts, finding words to use in a conversation, or keeping focus in a noisy environment.

When patients want help, they are often referring to functional improvements in areas such as:

  • Walking distance and endurance
     ● Hand control and fine motor consistency
     ● Walking and balance
     ● Mental clarity, stamina, and attention
     ● Recovery time (less “payback”) after an activity

These are the results that people see as restoring their lives.

Walking distance: Why endurance is often the real limiter

After a stroke, walking is more than just strength. It involves timing, coordination and balance. Many survivors are able to walk, but it is their endurance that breaks first.

  • Legs start to drag
  • The hip muscles spasm
  • Balance becomes unstable
  • The body stiffens
  • Fatigue increases

Some patients say that when circulation is improved and vascular function increases, they can go further before these breakdowns occur. A modest increase in endurance is a huge deal, as it allows for more repetitions in therapy and everyday life.

It’s also about neuroplasticity. Neuroplasticity refers to the brain’s ability to rebuild neural pathways, which, when strengthened with physical therapy, can have a tremendous effect on a patient’s ability to function. The brain can build more pathways if you do more quality repetitions. Working smarter and not harder is one key. Four 10-minute home PT sessions can be more effective than 60 minutes of overexertion and frustration.

Witness Edward Wilk’s inspiring journey of recovery after a cerebellum stroke. From using a walker to taking independent steps following Regenerative therapy at Kentuckiana Integrative Medicine.

Blood Flow and The Brain’s “Battery Life”

Sometimes, stroke patients report they can physically do the rehabilitation work but struggle with mental focus and stamina. Lumosity.com can help greatly as a tool with memory, focus and concentration.

  • brain fog
  • slow processing
  • short attention span
  • word-finding difficulty
  • fatigue in stimulating environments

The brain’s demand for oxygen and nutrients is high. When vascular health is compromised, especially in patients who also carry a heart disease history or plaque burden, cognitive stamina may be one of the first things to suffer.

Canadian Stroke patient Nancy Cyrenne is recovering from her stroke. After PSE – Perispinal Etanercept, Nancy experienced improvement in her mobility and walking abilities.

Integrative and Regenerative Therapy for The Brain-Heart Connection

Our approach is designed to address those contributors with therapies that support circulation, calm inflammation pathways, and improve the body’s capacity to participate in recovery.

Below are key therapies we offer to support stroke, heart, and vascular conditions.

PSE Perispinal Etanercept Therapy and Post-Stroke Inflammation

Perispinal Etanercept is used as a therapy to support stroke and neurological recovery. Decreasing brain inflammation signalling may help with chronic stroke symptoms that persist after initial brain injury. Our clinic has seen stroke patients recover the function of speech and balance even 15 years after a stroke. Perispinal Etanercept is not FDA-approved for stroke despite a tremendous amount of evidence proving beneficial effects.

When neuroinflammation is part of the therapy approach, patients may notice “rapid” improvements [within minutes] compared to the normal slow rehabilitation timeline. These improvements include clearer thinking, improved movement, improved walking and arm use and reduced pain patterns.

IV Chelation Therapy: Vascular Support and Heavy Metal Reduction

IV Chelation Therapy with EDTA can help support vascular health and bind heavy metals. Chelation goes parallel to cardiovascular and circulation conditions, such as:

  • Heart disease
  • TIA History
  • Peripheral artery disease
  • Cognitive decline and “brain fog” symptoms may overlap with vascular problems

NOTE – Chelation is NOT available in Kentucky since it was declared ILLEGAL in KY and three other states. Very few clinics in Indiana offer IV Chelation.

IV Plaquex (IV phosphatidylcholine / IV phospholipids): plaque and vascular resilience

IV Plaquex Therapy is described on our site as using phosphatidylcholine (a phospholipid) to support the body’s response to fatty plaque in vessels. This is often positioned as a complementary vascular-support approach, especially for people thinking long-term about:

  • Circulation
  • Endurance
  • cognitive clarity
  • cardiovascular risk factors that contribute to brain health

Many stroke survivors are living with both neurologic deficits and an underlying vascular dysfunction. Improving vascular function can be part of supporting brain function.

Regenerative injections and supportive therapy: removing barriers to rehab participation

Stroke recovery is often complicated by secondary issues: shoulder discomfort, hip pain, back pain, joint strain, and compensation patterns that build over time. Pain and restricted mobility can reduce participation and reduce repetition, slowing progress.

We may include regenerative injections as part of our overall regenerative medicine offerings. In practice, the goal is often to reduce pain-driven limitations and help people move more freely, so they can better engage in the physical therapy recovery work that matters most.

Hear for yourself what patients are saying. Below, find videos in which patients discuss their experience with our Regenerative Therapies.

Meet Mike Bonin, IT engineer, a stroke survivor, treated at Kentuckiana Integrative Medicine, bravely sharing his journey with paralysis, fine motor skill challenges, and balance issues. Despite daily struggles, Mike’s incredible resilience shines as he works towards regaining independence.

Louis Meier, 75-year-old Retired Mechanic Parkinsons who came to our office in a motorized wheelchair with advanced Parkinson’s, Lumbar Fusion, Severe Back Pain, Severe Hip Pain, Shuffling gate, Recurrent Falling for 6 months.

Dr. Alan Olo from Europe is a Stroke survivor who experienced prompt improvements with our therapies. Dr. Olo is the famous inventor of TRIGENIX, a therapeutic system known by many Physical therapists and Chiropractors.

REVERSE STROKE 60 MINUTES AUSTRALIA PERISPINAL ETANERCEPT: Connecticut teacher Linda received perispinal etanercept therapy and recovered speech and improves ability to walk 3 years after a massive stroke.

When a patient’s brain function improves, they want functional improvements:

  • How they feel and function today (walking distance, hand use, focus)
    ● How resilient their system is long-term (reducing the conditions that contribute to future vascular events)

Our Stroke Rehabilitation in Louisville is designed to go beyond physical therapy exercises alone. We look at the external and internal environment that influences performance and recovery capacity.

REGRETABLY INSURANCE CANNOT BE ACCEPTED as these therapies are NOT FDA approved, NOT covered by insurance who considers these therapies “experimental” in nature despite the wonderful evidence of tremendous benefits. Insurance pays only for conventional modern medicine. Strategies are considered experimental and not conventional. The approximate cost of the therapy for a full series of Heart IV Therapy is between $4,000 and $8,000, depending on the patient’s condition. IV Plaquex therapy costs $170, and IV chelation therapy costs $140. For most individuals $4,000 to $8,000 is a very reasonable investment in their health, as that is the sum spent on one vacation in many cases. We are very competitive as far as fees, as many clinics charge 2-4x more than we do.

What is meaningful progress? 

Stroke recovery doesn’t have to be dramatic. Most often, the most important wins are practical.

  • Walking further with less imbalance and more security
  • Transferring from chair to bed with greater ease
  • Using the affected hand or limb throughout the day
  • Conversations that are less mentally exhausting
  • Tolerating an activity without a crash of the whole day afterwards
  • Moving with more confidence in public places

These are the moments that can change your quality of life.

Stroke survivors often feel a change in their functional abilities when their brain inflammation is reduced. Supporting circulation can make rehab efforts even more effective: walking can be longer, hands can react more consistently, and focus can improve. Our integrative model addresses neuroinflammation and vascular health alongside rehabilitation principles.

Kentuckiana Integrative Medicine believes that stroke is more than just a neurological event. It is also an inflammatory event that can affect your function. Our goal is to create a plan for you that supports your brain, supports your vessels, and supports daily life functionality.

Other Therapies We Offer: We help patients reverse symptoms of Arthritis Joint and Spine Pain, Depression, Stroke, TBI, [Perispinal Etanercept] Parkinson’s, Heart Disease [IV chelation, IV phospholipids, Depression, PTSD, CRPS, IV Ketamine Therapy, Erectile Dysfunction, Stress Incontinence, BPH urinary frequency, Cancer Repurposed Therapies, IV Vitamin Therapy and IV Hydration. Hyaluronic Gel to arthritic Knees and Amniotic “Stem Cellular tissue products” Wound care covers for non-healing diabetic foot ulcers, venous stasis ulcers, Pressure Ulcers, Non-healing Surgical Wounds, and burns and much more. Discover what is possible at www.regenmedky.com 

Gary Robinson suffered from severe erectile dysfunction and stress incontinence, which was corrected with regenerative medicine injections.

Susan Johnson was oxygen dependent from her COPD until she tried our therapies. 

Dan and Paula Dalton from Washington State.

Dan had severe ED and uncontrolled high blood pressure, and Paula had severe ankle foot arthritis. 

FDA Disclaimer: All the Integrative Medicine therapies offered by Kentuckiana Integrative Medicine / Kentuckiana Neuro Recovery Center are considered experimental “off-label”, not covered by insurance and is not FDA-approved. The only exceptions are FDA approved and Traditional Medicare approved amniotic wound covers for non-healing diabetic foot ulcers and hyaluronic gel injections for arthritic knees, only offered by our affiliate Kentuckiana Medicine, not Kentuckiana Integrative Medicine / Kentuckiana Neuro Recovery Center. All content, including text and visuals, is for general informational purposes only and is not intended as medical advice. Please consult your medical provider to discuss what’s right for you. Results are variable. No guarantees of successful outcomes are made or implied, and individuals should not assume from video testimonials that they will respond favorably.

non-surgical heart treatment louisville

Can Heart Disease Be Reversed With Non-Surgical Heart Therapy in the Louisville Kentuckiana Area? YES

non-surgical heart treatment louisville

Regenerative Medicine by Dr. Rafael F. Cruz MD who has practiced medicine for 30+ years and is a physician educator researcher and inventor of Cruz Cric.

Dr. Rafael F. Cruz, MD board certified in Emergency Medicine twice, practiced Emergency Medicine for approximately 10 years. He received 2 years of anesthesia training with a focus on pain procedures at University of Louisville, and then he shifted his medical focus for the past 20 years to Integrative, Functional and Regenerative Medicine. The goal is optimal management and prevention of acute and chronic disease challenges.

Dr. Cruz is a founding member and fellow of the American Academy of Ozone Therapists and trained in IV Vitamin Therapy and IV Chelation via ACAM.org. ACAM is the American College for the Advancement in Medicine. He also trained at The Riordan Clinic in Wichita, Kansas on the uses of complementary IV Vitamin C and IV Ozone to help Cancer patients and those struggling with chronic immune dysfunction, like individuals with life syndrome. Dr. Cruz is a full-time clinician, educator, medical writer, student of medicine – life and an inventor of “cruzcric”, the only pocket emergency surgical airway device.

Dr. Cruz leads Kentuckiana Integrative Medicine, which follows a philosophy of combining the best of conventional modern medicine with natural integrative therapies. He is well known for his meticulous evaluations, collaborative therapies with primary and specialist providers, and image-guided precision with injured soft tissues: tendon injuries, shoulder rotator cuff tears, arthritic spines, joints, and ligaments. His services extend beyond musculoskeletal concerns to complex neurological and cardiovascular issues, hormone optimization and sexual wellness, support for sexual dysfunction and stress urinary continence, medical weight loss, and other specialized therapies. The clinic’s personalized plans and compassion are highly regarded by patients. Kentuckiana Integrative Medicine is a regenerative medicine clinic that has been providing regenerative therapies in Louisville and the wider Kentuckiana area for more than 20 years.

Heart disease is still among the top primary causes of death in the US, and many people want to know if they can get better without having to undergo major heart bypass surgery or heart stents. At Kentuckiana Integrative Medicine, our team focuses on providing complete cardiac support through a structured plan of IV therapies, nutrition, and lifestyle changes. We do NOT say we can cure you; instead, we want to help you stabilize your symptoms, improve your circulation, energy levels, and to help optimize your care in conjunction with your doctors. The clinic’s approach is based on 30+ years of clinical experience and research, such as the NIH-funded TACT study. Our non-surgical heart therapy is a thoughtful way for individuals to find a path to health that complements and enhances standard care approaches.

Regenerative medicine has provided many of our patients, including those with severe cases of bone-on-bone arthritis, with an avenue of much-needed pain relief and, in many cases, a restoration of the life activities they love.

REGRETABLY INSURANCE CANNOT BE ACCEPTED as these therapies are NOT FDA approved, NOT covered by insurance who considers these therapies “experimental” in nature despite the wonderful evidence of tremendous benefits.

Consultations are $300 paid in advance, but FREE and credited back to you if you invest $6,500+ in your health.

We do NOT sell your information like your Name, email and phone number.

We will NOT call you to schedule an appointment. PLEASE CALL OUR OFFICE.

You will need to call our office to schedule your appointment for an in person visit or from your home via Telemedicine Phone/Zoom. Your choice.

For a limited time, get $100 off your consultation fee with code “NRC2025.” Contact us today on 812-913-4416 or learn more at www.regenmedky.com.

HEART DISEASE REVERSED Dr Cruz Video Explaining IV Chelation and other servcies.

HEART DISEASE REVERSED with IV Chelation and IV Phospholipid Therapies explained by Dr. Cruz

Mary Lindel 85% Heart Artery blockage, Carotid Artery Blockage with Shortness of breath, Fatigue and Ankle swelling advised to have Bypass Heart Surgery by 2 Heart surgeons. 

 Neurological Injuries Reversed

Who Benefits From A Conservative Heart Program?

Many people who have stable symptoms and are not candidates for more invasive procedures or those with small heart vessel disease, as well as those recovering from previous cardiac events, who are seeking additional support. Research indicates that patients with diabetes may also benefit from risk-reduction strategies. We work closely to monitor, diagnose and support patient health goals with complementary therapies such as lifestyle modification, IV Plaquex and IV Chelation.

What “reversal” looks like in real life?

In practice, “reversal’ can be defined as slowing disease progression, improving function, and reducing symptoms. We monitor changes in energy levels, recovery time, fatigue, walking distance, exercise tolerance and chest tightness after exercise, as well as trends in cardiology and lab reports. These therapies are designed to help the body heal itself, not to replace prescribed medication or your cardiologist. We have demonstrated the reversal of heart disease using repeat cardiac catherization studies and repeat Heart plaque calcium scores, which have been lowered from 500 to 15 with an average of 60% reduction with 40 IV therapies. Patients with symptoms of chest pain or shortness of breath usually report relief of these symptoms after 10-20 IV Infusions.

Therapies Used At Kentuckiana Integrative Medicine

A core cardiovascular program can include IV EDTA chelation (with or without Plaquex), IV Vitamin C and IV Ozone. It may also include nutritional improvements, targeted supplements, and progressive exercise. EDTA chelation is a method that helps the body bind metals and eliminate them. Long-term exposure to lead and cadmium, for example, has been associated with increased cardiovascular risk and cancer. The TACT study used a 40-infusion protocol for patients who had a previous heart attack. It observed a statistically significant reduction in the composite endpoint of repeat heart attack, stroke and or death.

Chelation Therapy uses an amino acid, EDTA, in a solution containing vitamins and minerals to attach to heavy metals. They are then filtered out of the body through the kidneys in urine. Some integrative doctors have used chelation for over forty years to reduce symptoms such as heavy metal toxicity and heart disease. Chelation is intended to remove toxic metals, which are believed to have the potential to help the body reduce heart attacks, cardiac deaths, and the need for bypass surgeries and stents.

We use chelation as part of a structured therapy plan with sessions scheduled on a weekly basis during the initial phase. We also provide individualized dosages that consider kidney function and general health. Plaquex is a phospholipid that supports cellular membranes. Vitamin C provides antioxidant support. Ozone can be used to modulate the redox balance in an integrative setting. The benefits of these IV therapies can be compounded by combining them with plant-forward nutritional practices, reduced sugar consumption, hydration and restorative sleep.

Hear for yourself what patients are saying. Below, find videos in which patients discuss their experience with Chelation Therapy.

Mr. McCawley describes the transformation of his daily life and heart health that chelation therapy brought about. Mr. McCawley struggled with persistent brain fog and heart disease and was unable to cut his own lawn or climb stairs even after multiple heart stents. His symptoms improved so much after therapy that he quit his engineering job. He can now handle stairs, cut his own lawn, and has launched a landscaping company. 

Dr Robert Harris DDS discusses How Chelation Improved His Heart Disease with 3 vessels 95% coronary artery blockage with complete reversal after IV chelation. 

Sol Arledge – How Chelation Resolved My Atrial Fibrillation 

Ron Laughlin shared that a commercial vascular screen revealed a severely blocked carotid artery. Ron Laughlin, who wanted to avoid surgery immediately, began therapy at Kentuckiana Integrative Medicine with Dr. Cruz. He received approximately 20 IV chelation therapy and about 10 sessions of IV Plaquex. Upon rescreening, his carotid artery blockage was reduced from “critical” to “moderate.” He also reported improved energy and memory. Dr. Cruz said that patients with similar conditions benefit from increased blood flow to heart and brain. Most patients complete 40 IV chelation sessions. 

Greg Sanders from Mississippi, with a history of heart disease and high blood pressure, was unable to walk 20 feet without shortness of breath or chest tightness. Now he is  able to exercise without chest pain or shortness of breath after IV chelation and IV Plaquex for his heart disease. 

IV CHELATION for Mercury Toxicity; Cody’s Story. 

Progress is monitored through symptom journaling and functional measures, such as walking distance and ability to climb stairs. Relevant lab results are tracked, and care is coordinated with your cardiologist for imaging studies and follow-up evaluations. Weekly visits in the first phase ensure continuity and allow adjustments to be made based on tolerance. Patients often switch to less frequent maintenance IVs after the initial sequence while maintaining the same lifestyle principles. Durable outcomes are most often achieved when IV therapy is reinforced by consistent lifestyle practices, including nutrient dense, low glycemic food dietary intake, regular movement, stress management strategies, and proper sleep hygiene.

Every candidate undergoes a medical evaluation and labs before therapy. Sessions are provided under physician oversight, with dosing tailored to the individual. Therapies should continue unless your prescribing clinician changes them. We encourage routine cardiology care for blood pressure, lipid, and glucose management. Our aim is to help you feel and function better through steady, coordinated steps rather than quick fixes. For patients who value structure, a weekly schedule often supports the integration of healthy lifestyle changes.

NOTE – Chelation is rarely available in Kentucky since it was declared ILLEGAL in KY and three other states. Very few clinics in Indiana offer IV Chelation.

Dr. Rafael F. Cruz, MD of Kentuckiana Integrative Medicine, has been providing IV Chelation therapy in Kentuckiana for 20+ years. He is following in the footsteps of Dr. George Wolverton, MD, a Pioneer of Integrative Medicine in Kentuckiana, who was one of the first physicians to introduce IV Chelation to Kentuckiana. We remain the most experienced clinic in the area for complex medical challenges, where many are finding no answers via traditional medical channels. We hope you will share our information with the individuals you care about.

REGRETABLY INSURANCE CANNOT BE ACCEPTED as these therapies are NOT FDA approved, NOT covered by insurance who considers these therapies “experimental” in nature despite the wonderful evidence of tremendous benefits. Insurance pays only for conventional modern medicine. Strategies are considered experimental and not conventional. The approximate cost of the therapy for a full series of Heart IV Therapy is between $4,000 and $8,000, depending on the patient’s condition. IV Plaquex therapy costs $170, and IV chelation therapy costs $140. For most individuals $4,000 to $8,000 is a very reasonable investment in their health, as that is the sum spent on one vacation in many cases. We are very competitive as far as fees, as many clinics charge 2-4x more than we do.

Can Heart Disease Be Reversed With This Approach?

When a structured regimen of IV therapy and lifestyle changes is consistently followed, it is possible to see significant improvements in symptoms, strength, reduction of plaque blockage narrowing and quality of life. In many cases, risk markers will stabilize and show a positive trend. Others experience a gradual improvement in their functional abilities over several months. Some notice better energy levels and fewer symptomatic flare-ups. We encourage you to work to prioritize your health and be clear about your goals. Most patients are pleased with the transparency and benefits of our therapies. Those with diabetes or other risk factors for cardiovascular diseases may be more motivated to consider non-surgical heart therapies in Louisville, Kentuckiana. 

HEART DISEASE REVERSED with IV Chelation and IV Phospholipid Therapies explained by Dr. Cruz

If you’re ready to move forward, if possible, bring your most recent cardiac reports, lab testing, your current medication list and schedule a consultation. You can start with small wins, such as more walking, less refined sugar and better sleep, while your customized plan is developed. Our team will create a practical schedule, discuss costs, etc. Kentuckiana Integrative Medicine can help you determine if a conservative, integrated path is right for you. Connect with our clinic to learn more about a customized plan that focuses on symptom reduction, function and steady progress using IV therapy, nutrition and rehab activities.

Other Therapies We Offer: We help patients reverse symptoms of Arthritis Joint and Spine Pain, Depression, Stroke, TBI, [Perispinal Etanercept] Parkinson’s, Heart Disease [IV chelation, IV phospholipids, Depression, PTSD, CRPS, IV Ketamine Therapy, Erectile Dysfunction, Stress Incontinence, BPH urinary frequency, Cancer Repurposed Therapies, IV Vitamin Therapy and IV Hydration. Hyaluronic Gel to arthritic Knees and Amniotic “Stem Cellular tissue products” Wound care covers for non-healing diabetic foot ulcers, venous stasis ulcers, Pressure Ulcers, Non-healing Surgical Wounds, and burns and much more. Discover what is possible at www.regenmedky.com 

Gary Robinson suffered from severe erectile dysfunction and stress incontinence, which was corrected with regenerative medicine injections.

Susan Johnson was oxygen dependent from her COPD until she tried our therapies. 

Dan and Paula Dalton from Washington State.

Dan had severe ED and uncontrolled high blood pressure, and Paula had severe ankle foot arthritis. 

FDA Disclaimer: All the Integrative Medicine therapies offered by Kentuckiana Integrative Medicine / Kentuckiana Neuro Recovery Center are considered experimental “off-label”, not covered by insurance and is not FDA-approved. The only exceptions are FDA approved and Traditional Medicare approved amniotic wound covers for non-healing diabetic foot ulcers and hyaluronic gel injections for arthritic knees, only offered by our affiliate Kentuckiana Medicine, not Kentuckiana Integrative Medicine / Kentuckiana Neuro Recovery Center. All content, including text and visuals, is for general informational purposes only and is not intended as medical advice. Please consult your medical provider to discuss what’s right for you. Results are variable. No guarantees of successful outcomes are made or implied, and individuals should not assume from video testimonials that they will respond favorably.

regenerative therapy for hip pain in Louisville

Winter Spine and Joint Health: How Kentuckiana Regenerative Medicine Therapies for Spine and Joint Pain in Louisville Kentuckiana Support Cold Weather Pain Relief

regenerative therapy for hip pain in Louisville

Regenerative Medicine by Dr. Rafael F. Cruz MD who has practiced medicine for 30+ years and is a physician educator researcher and inventor of Cruz Cric.

Dr. Rafael F. Cruz MD listens to your health challenges before treating your symptoms. He is a two-time board-certified Emergency Medicine physician, a fellow founder of the American Academy of Ozone Therapy and Medical Director of Kentuckiana Integrative Medicine – Kentuckiana Medicine. His calm confidence stems from decades of medical experience. Dr. Cruz has dedicated his career to Integrative Medicine, combining the best of conventional modern medicine with natural regenerative restorative therapies. Dr. Cruz and his team help people move more comfortably and avoid surgery when possible. Dr. Cruz understands his patients’ struggles, examines their movements, reviews detailed diagnostics, and uses image guidance to help determine the source of the pain.

Dr. Cruz has been helping people in Louisville, Kentuckiana for more than 20 years, including active adults, grandparents and workers. He also helps those with fractures that have not healed or who are still suffering from pain after surgery. His expertise includes Photo energized, High Volume PRP, Prolotherapy, Prolozone and Personalized Messenger Signaling Cell therapies using a patient’s own tissue, as well as supportive options such IV Vitamin nutrient therapy. He is also an expert in neural therapy and supports patients with his personal, steady approach. Beyond musculoskeletal care, Dr. Cruz also brings experience with ozone based therapies, ketamine assisted protocols in select neurologic and pain conditions, hormone optimization, sexual wellness, stress urinary incontinence solutions, cardiovascular and neurologic support and evidence-based medical weight loss. Most patients will remember his kindness, the non-rushed explanations, the practical therapy plans he customizes for each patient.

Regenerative Medicine has provided many of our patients, including those with severe cases of bone-on-bone arthritis, with an avenue of much-needed pain relief and restoration to the life they love. Consultations are $300 paid in advance, but FREE and credited back to you if you invest $6,000+ in your health. We do NOT sell your information, and we will NOT call you to schedule an appointment. You will need to call our office to schedule your appointment in person or via Telemedicine Phone/Zoom.

For a limited time, get $100 off of your consultation fee with code “NRC2025”

Contact us today on 812-913-4416 or learn more at www.regenmedky.com.

Why Winter Worsens Joint and Spine Pain

Many people in Kentuckiana feel the temperature drop first in their hips, knees, shoulders and spine. Cold air, lower pressure and tighter tissues can all combine to increase stiffness and limit the range of movement. Winter can make it difficult to move, especially for active adults and older adults with osteoarthritis. It is also a problem for those recovering from joint and or spine strains or hip or shoulder labral irritation. Our clinical focus is to provide precision, evidence-based care that supports the body’s self-healing response, while also protecting joint function. Many patients are looking for alternatives to pain medication and repeated steroid injections. Regenerative therapies for joint and spine pain in Louisville, Kentuckiana is a non-surgical option worth considering in most cases. Regenerative Medicine therapies aim to support tissue repair and calm localized inflammation.

Cold weather can affect joints, spine and soft tissue in several different ways. When exposed to colder temperatures, muscles and tendons tighten, causing joint compression. This can make movements feel “sticky” or stiff, especially after prolonged sitting or in the morning. Shifts in barometric conditions can affect the way tissues contract and expand, which is why some people feel a deep, achy feeling in their joints, spine, hips or groin. Winter routines can reduce the amount of time you spend moving and increase your time sitting. This affects circulation and nutrient delivery, which Musculo-skeletal tissues need to function and feel healthy.

These seasonal stressors may trigger symptoms of osteoarthritis or other conditions, such as gluteal tendinopathy. It is good to know that you can make a difference in your everyday life. The combination of a smart gentle warm-up before exercise, regular mobility exercises, strengthening hip stabilizers and wearing layers to protect the hips from the cold can reduce flare-ups. Combining these habits with targeted biological therapies can provide additional support for many patients during the coldest months.

Our team at Kentuckiana Integrative Medicine RegenMedKy.com emphasizes an accurate diagnosis, as well as a step-by-step therapy plan. Our team begins by evaluating the location of your pain, aggravating movements (such as walking, stair climbing, pivoting or prolonged sitting), as well as gait patterns and strength imbalances. Imaging is often an ultrasound to assess dynamically, and, if needed, an MRI can help guide precise ultrasound-assisted injections. It also helps rule out or in key pain generators like the joint, the bursa, the tendons or the labrum.

Dr. Rafael Cruz MD explains that Kentuckiana Integrative Medicine provides image‐guided regenerative care using a patient’s own biologics. The clinic harvests cells from belly fat or bone marrow (with optional lab expansion for future use) or use commercial biologics which support the body to improve advanced arthritis, tendon/ligament tears, nerve injuries, and other tough cases, often helping patients avoid surgery. We often start with Prolotherapy/Prolozone for mild issues, use Photo-energized, High Volume PRP for moderate problems, and reserve “stem” cellular regenerative injection therapies for severe cases.

Dr. Cruz also shares that Traditional Medicare covers 100% of hyaluronic acid gel injections for arthritic knees only. Medicare will not cover other joints. All injections are ultrasound/fluoroscopy‐guided for precise placement

How Regenerative Medicine Approaches Regenerative Care in Cold Weather

Kentuckiana Regenerative Medicine prioritizes non-surgical image-guided procedures to target the structure in the joint or spine responsible for causing pain. Whenever needed we use ultrasound and or fluoroscopy to place the therapy into the joint, the gluteal tendon, or the bursa.

The following are our core biological options:

  • Prolotherapy is used to strengthen painful ligaments & tendons.[B vitamins, dextrose, procaine]
  • Prolozone is used to strengthen painful ligaments and tendons. [Oxygen with a 3rd atom]
  • Platelet-Rich Plasma Concentrates Growth Factors
  • Cellular Biological Messenger Signaling therapies which send a repair signal to the cartilage, capsule and peritendinous tissues.

Winter stiffness won’t stop you from making progress. Each plan includes a combination of short warm-ups and heat before movement. Many patients choose regenerative medicine therapy for joint and spine pain in Louisville instead of waiting for surgery or repeating steroid injections.

What PRP Platelet Rich Plasma Can Do for Winter Joint and Spine Pain?

PRP is derived from a small blood sample and concentrated to deliver signaling proteins where they are most needed. Intra-articular Joint PRP can modify inflammatory pathways in hip osteoarthritis, alleviating morning “start-up” pain. Peri-tendinous PRP around the gluteus medius/minimums may alleviate lateral hip pain, which worsens with cold and prolonged sitting. Most patients walk on the same day, following a simple pacing plan that focuses on circulation without overload.

Prolotherapy and Prolozone: Promote Joint and Spine Stability

Prolotherapy/Prolozone can be beneficial for symptoms caused by discomfort at ligament or tendon insertions. These injections promote a localized healing response at attachment sites, improving stability and reducing discomfort throughout the injected area.

To prevent slip-related injuries during winter, we recommend combining these therapies with physical therapy. In the case of hip pain, we recommend lateral hip strengthening, short-stride drills for snowy days, and balancing exercises.

Personalized Messenger Signaling Cell Therapy

In some circumstances, we use a patient’s own biologic materials to transmit signaling cells to the joint or surrounding soft tissues or commercial products. When needed Image guidance guarantees proper placement. The goal is to aid in tissue regeneration in difficult-to-heal locations, including cartilage surfaces, capsular tissue, and chronically inflamed tendons, while minimizing downtime. Walking is frequently encouraged on the same day, with a controlled development over the next few weeks.

Please watch the numerous unpaid testimonials below to discover all your available options.

We like to say: “Discover what is possible. The impossible is sometimes possible with the right approach.”

Hear from our patients:

Martin Wilks recovers from a stroke that left him with imbalance-difficulty walking, speech and memory difficulties. Here he is fully recovered after regenerative therapies including etanercept.

Cindy Moore: Cindy’s Rapid Turnaround with Regenerative Care Injections after 2 failed Lumbar surgeries left her crippled. After years of escalating pain and relying on a cane, Cindy followed a customized plan, including an MRI-guided evaluation, targeted injections, and expanded personal “stem” cellular regenerative injection therapies. Watch Cindy share how she went from 1 block and 5-minute limits to hours of comfortable walking and standing. From cane to living pain-free. Cindy followed a personalized, MRI-guided plan and now walks and stands comfortably for hours. Within 4 weeks of receiving regenerative medicine injections, Cindy was able to go sightseeing in Europe pain FREE. If chronic pain is stopping you, you don’t have to live with it.

Our patient, Melaine Drury [a Kentuckiana Nurse Practitioner], discusses how NINE years of Severe Neck & Back Pain were relieved with Messenger Signaling “Stem” Cellular Therapy, Platelet Rich Plasma, Prolotherapy, and Prolozone.

Nancy Purvis had bilateral severe knee arthritis. She had sever pain pressing on her car gas pedal, steps, walking, getting in out of chair or her car. Most of her relatives had had knee replacement surgery which she did not want. With regenerative medicine injections she now golfs regularly pain free sometimes 2-3 x per week.

Mark Brooks, 52 years old, was diagnosed with severe left hip osteoarthritis and he was advised that his only solution was hip replacement surgery. He walked with a cane, and orthopedics told him that surgery was the only option. In just six weeks, Mark Brooks’ pain gradually subsided. Within eight to nine months, he returned to strenuous activity and even completed his Colorado bucket list trip which was hiking, prospecting and panning for gold. He returned to Kentuckiana Integrative Medicine in order to address his right hip condition. Four years after the initial therapy, his left hip remains strong and only occasionally twinges.

Gayle Pohn 86-year-old retired attorney with severe shoulder arthritis and rotator cuff tears dramatically improved with Regenerative Medicine Messenger Signaling Stem Cellular and PRP Platelet Rich Plasma Injection therapies. Even his golf game improved.

Joseph Williams accelerates the healing of his knee surgery in days.

Dr. Chris Rasmussen was having trouble walking at work due to severe knee pain. He experienced complete relief after his regenerative medicine injections.

Bobby Dean 73 years old cancer survivor goes skiing after receiving 5 hyaluronic gel injections to his arthritic knees which he is entitled to receive this therapy every 6 months at no charge.

How long can Regenerative Medicine Therapies last?

Dr. Cruz says that PRP therapy can be effective for up to five years, and “stem” cellular regenerative injection therapies for may be helpful for five and ten+ years depending on patient health, level and type of activity, sugar and carbohydrate avoidance and trauma avoidance.

Kylie is a competitive runner who suffered from severe hip and pelvic osteochondritis. Despite seeing multiple doctors and having imaging done, she did not find relief with all her previous doctors and therapists. She was able to resume training after just two PRP sessions, followed by five Prolozone therapy sessions with Dr. Cruz. By the fifth session, she was pain-free and able to compete on a collegiate level. She received a running college scholarship after receiving regenerative medicine injections at Kentuckiana Integrative Medicine. 

The patient had previously been off work for over a year, with intermittent periods of improvement, and had been off for three months when he began therapy. After just one session of Prolozone therapy, he returned to working 60+ hours per week. The improvement lasted four months, with some pain returning, though much less severe than before. He is now seeking a “tune-up” session to maintain his ability to work.

Not every joint and spine pain issue requires biological regenerative medicine procedures. We confirm the true pain generator with examination and imaging when needed, then match the therapy to the situation: joint (Prolozone, Prolotherapy, PRP or signaling cellular therapies), bursa (targeted injection with anti-irritant strategy), or tendon/ligament (PRP or Prolotherapy/Prolozone). People with osteoarthritis or bursitis are ideal candidates. They may also have rotator cuff shoulder tears, labral-related tears, irritation, osteoarthritis or osteochondritis. The expectations and milestones will be discussed upfront so that progress can easily be tracked.

Safety, Precision, and Recovery Essentials

The treatment is performed using a sterile technique with if needed real-time imaging in order to protect nearby structures. Using PRP and Mesenger Mesenchymal Cellular biologics can ensure compatibility and reduce infection risks.

Winter-smart habits are key to recovery: short, frequent walks, applying heat before moving, traction-friendly shoes, and progressive strengthening of the deep rotators, as well as the lateral hip. Our physical therapist will work with you to ensure that your joint and spine pain are treated effectively during the colder months.

Schedule a focused assessment if cold snaps limit your sleep, walking, bending, carrying or steps. We will identify the pain source and outline whether PRP, Prolotherapy/Prolozone, or personalized messenger signaling cell therapy alone or in sequence fits your goals. Regenerative therapy for joint and spine pain in Louisville, along with warm-ups, hydration and graded strength can help you move more freely and confidently all winter and summer.

Other Therapies We Offer:

We help patients reverse symptoms of Stroke, TBI, [Perispinal

Etanercept, Parkinson’s, Heart Disease, IV chelation, IV phospholipids, Depression, PTSD, CRPS, IV Ketamine Therapy, Female and Male Sexual Wellness, Erectile Dysfunction, Stress Incontinence, BPH urinary frequency, Cancer Repurposed Medications, IV Vitamin Therapy and IV Hydration, Amniotic Wound care covers for non-healing diabetic foot ulcers and much more.

Discover what is possible at www.regenmedky.com

Gary Robinson suffered from severe erectile dysfunction and stress incontinence, which was corrected with regenerative medicine injections

Suan Johnson was oxygen dependent from her COPD until she tried our therapies.

Dan had severe ED and uncontrolled high blood pressure, and Paula had severe ankle-foot Arthritis.

Kentuckiana Integrative Medicine Overview:

FDA Disclaimer: All the Integrative Medicine therapies offered by Kentuckiana Integrative

Medicine / Kentuckiana Neuro Recovery Center are considered experimental “off-label”, not covered by insurance and are not FDA-approved. The only exceptions are FDA-approved and Traditional Medicare approved amniotic wound covers for nonhealing diabetic foot ulcers and hyaluronic gel injections for arthritic knees, only offered by our affiliate Kentuckiana Medicine, not Kentuckiana Integrative Medicine / Kentuckiana Neuro Recovery Center. All content, including text and visuals, is for general informational purposes only and is not intended as medical advice. Please consult your medical provider to discuss what’s right for you. Results are variable. No guarantees of successful outcomes are made or implied, and individuals should not assume from video testimonials that they will respond favorably.

imageedit_18_7515132010

Regenerative Arthritis Treatment Clinic Louisville, serving Kentuckiana: Early Signs of Osteoarthritis and When to Seek Care

Regenerative Medicine by Dr. Rafael F. Cruz MD who has practiced medicine for 30+ years and is a physician educator researcher and inventor of Cruz Cric.

Dr. Cruz is a founding member and fellow of the American Academy of Ozone Therapy and board‐certified in Emergency Medicine twice. His philosophy blends the strengths of conventional modern medicine with evidence‐informed integrative approaches, aiming to reduce symptoms, restore function, encourage self-healing and help patients avoid unnecessary surgery whenever possible. Dr. Cruz’s therapies have helped patients who are still in pain after surgery or have bones that refuse to mend or fuse together after surgical alignment. Dr. Cruz partners closely with each patient and their primary providers, using precise image guidance to target injured joints, ligaments, and soft tissues. Beyond musculoskeletal care, he treats complex neurological and cardiovascular conditions, offers hormone optimization, sexual wellness-stress urinary incontinence therapies and medical weight‐loss services, as well as specialized therapies. Patients value his thorough evaluations, personalized plans, and the clinic’s breadth of regenerative options delivered with accuracy and compassion. Dr. Cruz uses both conventional modern medicine and natural methods to help patients move more confidently and with less and often no joint or spine pain. Kentuckiana Regenerative Medicine has offered regenerative medicine therapies for joint, spine, hip, shoulder and knee pain in Louisville and Kentuckiana for over 20 years.

Osteoarthritis is a gradual condition that develops as the protective cartilage wears down and the joint becomes inflamed. Many people experience a dull ache following activity, morning stiffness that sometimes subsides in 30 minutes or a clicking/grinding feeling when moving. Common symptoms include swelling after long walks, difficulty fully straightening your knee and tenderness at the joint line. The joint capsule, surrounding muscles, and ligaments may compensate for these changes, which often come in waves. Ignoring these clues may allow inflammation to damage tissues, leading to joint pain and mobility loss.

Our leading regenerative arthritis treatment clinic in Louisville, Kentuckiana focuses on nonsurgical alternatives to alleviate pain, improve function, and help you delay or prevent joint replacement. Patients seeking regenerative therapy for brain dysfunction, spine, joint, hip, shoulder and knee pain in Louisville, as well as those from across the United States and as far away as Canada and Europe, choose our clinic for its proven results. 

Regenerative medicine has provided many of our patients, including those with severe cases of bone-on-bone arthritis, with an avenue of much-needed pain relief and a restoration to the life they love. Consultations are $300 paid in advance, but FREE and credited back to you if you invest $6,000+ in your health. We do NOT sell your information, and we will NOT call you to schedule an appointment. You will need to call our office to schedule your appointment in person or via Telemedicine Phone/Zoom.

For a limited time, get a $100 off consultation with code “NRC2025”

Contact us today on 812-913-4416 or learn more at www.regenmedky.com

When discomfort makes it hard to climb stairs, get out of a chair, or grasp a doorknob, it’s time to seek medical attention. Night stiffness that wakes you, frequent swelling after exercise, or a feeling of instability indicate that the joint should be evaluated and likely would benefit from therapy. Another crucial sign is a loss of trust in movement; you move less because you’re afraid the joint will “give way.”

That deconditioning may accelerate wear and arthritis development. At the start of your care journey at Kentuckiana, our team conducts a thorough examination and will provide a comprehensive plan.

Why Precise, Non-Surgical Care Helps

Not every type of osteoarthritis is the same. Some individuals experience synovial inflammation, while others experience microtears in their tendons and ligaments, leading to joint irritation. Looking into the causes, we can modify therapy to reduce inflammation, promote tissue healing, and restore mechanics.

A holistic approach is generally an effective therapy for mid-stage osteoarthritis. Weight control, reduced activity, and focused physical therapy can all help minimize joint load. Bracing for the knee, foot alignment support, and mobility exercises keep you moving while your tissues repair. Our image-guided regenerative therapies target the painful anatomy to promote healing and increase comfort when conservative treatments are insufficient.

According to Dr. Rafael Cruz, MD, fluoroscopy-guided hyaluronic gel injections for arthritic knees and shoulders accurately deliver cushioning and lubrication into the joint, unlike “blind” injections, which have been shown in research to miss the joint up to 30% of the time. This accuracy enhances pain alleviation and function while also providing regenerative effects. Traditional Medicare typically covers 100% a five knee injection series (one per week), with the option to repeat every six months if needed. Other joints can be treated affordably on a self-pay basis.

Accelerated Knee Healing after Surgery Joseph Williams

Therapies We Offer:

Platelet-Rich Plasma (PRP) therapy uses growth factors using a concentrated portion of your own platelets. PRP helps the body’s own healing process by calming inflammation, stimulating repair of tendons, ligaments and cartilage surfaces. In our clinic, we photo-energize your PRP making it more effective. When needed, we use injections under ultrasound or fluoroscopic supervision to ensure the solution is delivered precisely where it is needed. As the biological effect builds, many patients experience significant improvements – less or no joint pain and a smoother range of motion over several weeks or months.

Personal Harvested Messenger Signaling “Stem” Cellular Injections provide biologic signals derived from cells that modulate inflammation pathways and help the tissue self-repair within the joint. These signals can help the body reduce soft-tissue irritation and promote a balanced joint environment. As inflammation subsides and tissues self-repair, patients often report dramatic improved functionality and fewer or no pain flare-ups. Often they return to the activities they love, such as walking, golf, tennis and picking up the kids.

Hyaluronic “Knee Gel” injections help restore lubrication and add cushioning and likely stimulate some growth of cartilage in arthritic knees. Knee gel also aids in reducing pain and discomfort during everyday activities, such as walking, climbing stairs or standing longer. Combining knee gel with biologic therapies such as PRP can offer enhanced benefits.

Prolotherapy/Prolozone targets lax or irritated ligaments that contribute to instability and pain. Dextrose injections, sometimes combined with ozone to stimulate self-healing, can support strengthening of connective tissue. A better ligament support can improve alignment and reduce mechanical strain on the joint. This may lessen pain.

Please watch the numerous unpaid testimonials below to discover all your available options. We like to say ‘Discover what is possible. The impossible is sometimes possible with the right Approach.”

Cindy Moore experienced Failed Surgery Back Syndrome after 2 lumbar Spine surgeries left her crippled and in pain with just washing her hair or standing for 5 minutes. With Regenerative Medicine injections she is now pain-free and active.

Murdanye Nichols was advised to have lumbar spine surgery as her only option. She refused and chose regenerative medicine injections.

Dr. Chris Rasmusen was advised to have knee surgery as his only option. He refused and chose regenerative medicine injections.

Brian Folz was advised to have knee surgery as his only option. He refused and chose regenerative medicine injections.

Nancy Purvis had extremely painful knees that made her feel crippled. After regenerative medicine injection therapy, she plays golf regularly.

Bobby Dean in his 70s had severe knee arthritis. After Hyaluronic Gel Injections to his knees he was able to go skiing.

Ms. Norcross arrived with severe pain resulting from a non-healing femoral condyle fracture, stage 4 knee arthritis, a meniscus tear, and an ACL tear. She was using a walker. By her fourth hyaluronic gel injection, she no longer needed the walker and was able to take the ten steps to her basement, allowing her to resume her favorite activity, doing laundry.

Rhonda was diagnosed with severe tarsal-tunnel syndrome. After steroids and shoe changes failed, she was scheduled for surgery. After two Prolotherapy/Prolozone therapies, her pain eased, mobility returned, and she cancelled surgery–results that have lasted about seven years. She continued to be active as an artist and teacher, receiving an injection for an upper arm strain. Recently, she sought therapy for her lower back.

For roughly a year, Mr. Noble’s right knee arthritis kept him from standing longer than an hour, with pain at 8/10. Following four fluoroscopy-guided hyaluronic gel injections, his pain dropped to 1/10 and he can now stand three to four hours, climb stairs, and get in and out of a car with little difficulty. He’s proceeding with a fifth injection to build on these gains. Using fluoroscopic X‐ray guidance ensures the medication is placed exactly in the joint, avoiding the inaccuracies of blind injections.

As an established regenerative arthritis treatment clinic in Louisville, serving Kentuckiana, our procedures are image‐guided [if needed] to maximize accuracy and minimize discomfort. We tailor dosing, placement, and the sequence of therapies to your goals, like returning to tennis, hiking with grandchildren, or simply standing and cooking dinner without joint pain. We also coordinate with physical therapy to reinforce gains in stability, strength, and gait mechanics so improvements last.

When should you seek care? If symptoms have persisted more than a few weeks, if over‐the‐counter strategies no longer help, or if you find yourself avoiding activities you enjoy, schedule a consultation. Earlier attention often means simpler interventions and better outcomes. Our team will review imaging, examine movement patterns, and guide you through a plan that may include PRP, Personal Harvested Messenger Signaling “Stem” Cellular Injections, Hyaluronic Knee Gel Injections, or Prolotherapy/Prolozone, are selected for your personalized therapies. Mid‐course checks allow us to adjust the plan, ensuring sustained relief from joint pain and a steady return to confident movement.

With thoughtful diagnostics and image‐guided regenerative care, many patients experience less stiffness, improved function, and fewer flares. If you’re looking for a partner in nonsurgical relief, choose our regenerative arthritis treatment clinic in Kentuckiana for personalized options that help you move with less joint pain and more freedom.

Other Therapies We Offer: We help patients reverse symptoms of Stroke, TBI, [Perispinal Etanercept] Parkinson’s, Heart Disease [IV chelation, IV phospholipids, Depression, PTSD, CRPS, IV Ketamine Therapy, Erectile Dysfunction, Stress Incontinence, BPH urinary frequency, Cancer Repurposed Medications, IV Vitamin Therapy and IV Hydration, Amniotic Wound care covers for non-healing diabetic foot ulcers and much more. Discover what is possible at www.regenmedky.com 

Gary Robinson suffered from severe erectile dysfunction and stress incontinence, which was corrected with regenerative medicine injections.

Suan Johnson was oxygen dependent from her COPD until she tried our therapies.

Dan and Paula Dalton from Washington State. Dan had severe ED and uncontrolled high blood pressure, and Paula had severe ankle foot arthritis.

FDA Disclaimer: All the Integrative Medicine therapies offered by Kentuckiana Integrative Medicine / Kentuckiana Neuro Recovery Center are considered experimental “off-label”, not covered by insurance and is not FDA-approved. The only exceptions are FDA approved and Traditional Medicare approved amniotic wound covers for nonhealing diabetic foot ulcers and hyaluronic gel injections for arthritic knees, only offered by our affiliate Kentuckiana Medicine not Kentuckiana Integrative Medicine / Kentuckiana Neuro Recovery Center. All content, including text and visuals, is for general informational purposes only and is not intended as medical advice. Please consult your medical provider to discuss what’s right for you. Results are variable. No guarantees of successful outcomes are made or implied, and individuals should not assume from video testimonials that they will respond favorably.

wound care doctor

Wound Care Clinic Near Me in Jeffersonville, IN Serving Louisville Patients

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Our wound care clinic in Jeffersonville, Indiana, just minutes from Louisville, was built for people who are tired of that cycle. We provide full wound care services for Medicare patients and most major private insurance plans, and our focus is not just short term wound management but long term healing. That means using the proper standard of care first, and if the wound does not respond, digging deeper and bringing in more advanced options to actually fix what is holding your body back from healing.

We believe wound care should not feel endless. Our goal is to resolve the wound and reduce the chance that it comes back again.

Why people search for a wound care clinic near me

Most people do not plan to become wound care patients. It usually starts with something small. A blister on a diabetic foot. A scrape that does not close. A surgical incision that keeps draining. A sore on the leg that looks minor at first and then slowly grows. Weeks later, the wound is still there, and now it hurts, smells, leaks, or looks angry.

That is the moment when people type “wound care clinic near me” into their phone.

If that sounds familiar, you are not alone. Chronic wounds affect millions of people every year. Diabetes, circulation problems, nerve damage, swelling, limited mobility, and even something as simple as poor shoe fit can turn a small injury into a long term problem. The good news is that with proper wound care, many of these wounds can heal. The bad news is that without the right plan, they often do not.

Who we treat

At our Jeffersonville wound care clinic, we see patients from across Southern Indiana and the Louisville area with all types of wounds, including:

  • Diabetic foot ulcers
  • Venous leg ulcers from poor circulation or swelling
  • Pressure injuries or bed sores
  • Surgical wounds that are slow to close
  • Traumatic wounds from falls, cuts, or accidents
  • Infected wounds
  • Wounds that reopen again and again
  • Wounds complicated by neuropathy or limited blood flow

Whether the wound is new or you have been dealing with it for months, a focused wound evaluation can make a big difference.

When you search for a “wound care clinic near me,” what you are really looking for is not just a place that can change a bandage. You are looking for answers. Why is this wound still open? Why does it keep getting infected? Why did it heal a little and then stall? Why do I keep coming back every week with the same problem?

What full service wound care really looks like

Many people think wound care is just cleaning a wound and covering it. In reality, effective wound care is a system. It includes careful evaluation, consistent treatment, and adjustments based on how your body responds.

At our clinic, your care typically includes:

A detailed wound assessment
We measure the wound, look at the tissue, check for signs of infection, evaluate drainage, and assess the skin around it. This creates a baseline so we can track progress and know if something is not working.

Debridement when needed
Removing dead or unhealthy tissue can be critical. It reduces bacteria, allows oxygen and nutrients to reach healthy tissue, and gives the wound a chance to start healing again.

Infection control
Some wounds are stuck because bacteria or biofilm keeps them inflamed. We use topical treatments, cultures when necessary, and coordination with your other doctors if systemic antibiotics are required.

Advanced dressings
Different wounds need different moisture levels. Too dry and tissue cannot grow. Too wet and the wound breaks down. We select dressings based on the wound, not just what is on the shelf.

Compression for leg wounds
If you have swelling in your legs, especially with venous ulcers, compression is often the key to healing. Without controlling swelling, wounds struggle to close.

Pressure relief and offloading
Foot wounds in particular do not heal if you keep walking on them the same way. We work with offloading devices and strategies to protect the wound between visits.

Ongoing monitoring and adjustment
Wounds change. What worked last week may not be right this week. We adjust your plan based on how your wound responds.

This is the standard of care that every wound patient deserves.

When standard care is not enough

Here is where many wound care stories go wrong. A patient receives basic wound care for weeks or months, but the wound never really improves. The same dressing is used. The same routine continues. Nothing changes.

Our protocol is different. We start with proper standard wound care. But if the wound is not improving on a reasonable timeline, we step back and ask why.

  • Is there poor circulation that is starving the tissue?
  • Is swelling crushing the small blood vessels?
  • Is pressure or friction reopening the wound every day?
  • Is there a hidden infection?
  • Is blood sugar control interfering with healing?
  • Is nutrition part of the problem?

Once we identify the reason the wound is stalled, we can match the treatment to the real problem. This may include more advanced wound therapies, deeper diagnostic work, or collaboration with other specialists. We also offer regenerative focused treatments when appropriate to support tissue healing and address the underlying causes that keep wounds coming back.

The goal is not to keep you in a treatment loop. The goal is to get you healed and keep you that way.

Medicare and insurance coverage for wound care

Many patients worry about whether wound care is covered. The good news is that Medicare and most private insurance plans cover medically necessary wound care.

Medicare Part B typically applies to outpatient wound care visits, physician services, and many wound related treatments. Medicare may also cover home health services when a patient qualifies and needs skilled nursing for wound care at home.

Private insurance plans usually cover standard wound care and often cover advanced therapies when medical necessity criteria are met. Every plan is different, but our team works with your insurance to make sure care is documented properly and aligned with coverage rules.

If you are a Medicare patient or have private insurance and are searching for a wound care clinic near me, we can help you understand what is covered and what to expect before treatment begins.

Why location matters

Being close to your wound care clinic matters more than people think. Wound care is not a one time visit. It often requires regular follow ups, especially in the early stages. Our Jeffersonville location is convenient for patients throughout Clark County and across the river in Louisville. That means less travel, less stress, and better consistency with care, which leads to better healing.

If you are searching for a wound care clinic near me and live in Southern Indiana or the Louisville area, you do not need to travel far to get comprehensive care.

What happens at your first visit

Your first visit is focused on understanding your wound and your health as a whole. We will:

  • Review your medical history and medications
  • Examine and measure the wound
  • Check for infection or circulation issues
  • Discuss how the wound started and how it has been treated
  • Explain what we see and what it means
  • Create a treatment plan designed for your specific wound

You will leave knowing what is going on and what the next steps are. No guessing. No vague answers.

When to book a wound care appointment

You should not wait if:

  • Your wound has not improved in two to four weeks
  • You have diabetes and any foot wound
  • The wound is red, painful, draining, or smells bad
  • You keep getting the same wound in the same spot
  • You have swelling in your legs with an open sore
  • A surgical wound is not closing

These are signs that the wound needs more than basic care.

Chronic wounds usually do not heal because something is blocking the process, not because you are doing something wrong
Standard wound care is important, but if a wound is not improving, the plan must change
Medicare and most private insurance plans cover medically necessary wound care
Advanced treatments and deeper evaluation can make the difference when wounds stall
Our goal is healing and long term stability, not endless visits

FAQ

Do you accept Medicare for wound care?
Yes. We treat Medicare patients and provide the documentation needed for covered wound care services.

What kinds of wounds do you treat?
We treat diabetic foot ulcers, leg ulcers, pressure sores, surgical wounds, infected wounds, and more.

How often will I need to come in?
This depends on the wound. Some patients need weekly visits at first, others less often as the wound improves.

Will it hurt?
Some procedures like debridement can cause discomfort, but we work to keep you as comfortable as possible and explain everything before we begin.

What if my wound has not healed with previous treatment?
That is exactly when a wound focused clinic can help. We look for the reasons the wound is stalled and adjust the plan.

Do you work with private insurance?
Yes, we work with most major private insurance plans.

How do I get started?
Call our office or request an appointment online to schedule your first wound care consultation.

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Regenerative Medicine for Joint Pain at Kentuckiana

Regenerative Medicine by Dr. Rafael F. Cruz MD who has practiced medicine for 30+ years and is a physician educator researcher and inventor of Cruz Cric.

Living with joint pain—whether in your knees, hips, shoulders, or hands—can affect every aspect of life. Simple tasks become challenging, sleep suffers, and favorite activities fade into memory. For years, standard treatments like painkillers, steroid injections, or surgery have been the go-to solutions. But a new approach is gaining attention: regenerative therapy.

This isn’t science fiction—it’s a medical field focused on repairing and restoring damaged tissues. Instead of merely reducing inflammation or dulling pain, regenerative therapy works at the cellular level to stimulate the body’s natural healing processes.

One of the most widely discussed methods is platelet-rich plasma (PRP) therapy. Using your own blood, PRP concentrates platelets—key players in tissue repair—into a potent serum injected directly into the affected joint. The aim is to trigger a repair response, which for some patients has meant improved mobility, reduced stiffness, and less reliance on medication.

Another promising technique involves mesenchymal stem cells, often sourced from bone marrow or fat tissue. These cells have the potential to regenerate cartilage and reduce inflammation. While many patients report positive outcomes, regenerative therapy is not a miracle cure. Age, the extent of joint damage, overall health, and immune function all influence results—and what works for one person may not work for another.

Two of the most recognized therapies—platelet-rich plasma (PRP) and messenger signaling stem cellular injections—work by delivering concentrated growth factors or healing cells directly to the injury site, aiming to speed recovery and restore function.

The difference at Kentuckiana Regenerative Medicine is experience, thoroughness and advanced techniques. We are one of the few clinics that can harvest messenger signaling stem cellular tissues from abdominal fat and bone marrow. We draw 10x more blood than the average PRP clinic resulting in more PRP. We then enhance the PRP with Vitamins, Procaine and we photo-energize the PRP. In addition, we give all patients IV Vitamin therapy which enhances our results.

Brian Folz- Regenerative Medicine Stem Cellular Knee Injections: Brian UPS Delivery driver with knee meniscus tear and severe pain was advised to have knee surgery. After receiving regenerative medicine injections instead of surgery, Brian for years now has been in and out of his truck daily delivering packages and he is still pain free. He even jumps on a trampoline with his children.

Joseph Williams – Heals knee much faster than normal

Dr. Chris Rasmusen, DC Severe knee arthritis (history of knee fracture and meniscus surgery) responded to regenerative medicine injections and avoided surgery.

Because these treatments are still relatively new, discussing them with your doctor is critical. An accurate diagnosis is the first step, followed by a clear understanding of whether regenerative therapy is appropriate for your specific condition—whether it’s osteoarthritis, a past injury, or an autoimmune issue.

What’s most exciting is the shift in mindset: moving from simply managing pain to actively supporting the body’s ability to heal itself. For many, that represents hope—a chance to reclaim mobility and reduce discomfort without relying solely on pills or surgery.

If you’re considering regenerative therapy for joint pain, take the time to research, ask questions, and consult a trusted medical professional. Trends in medicine don’t always align with what’s right for you—but when they do, the possibility of moving freely and living with less pain may be closer than you think.

FDA Disclaimer: All the therapies offered by Kentuckiana Integrative Medicine/ Kentuckiana Neuro Recovery Center are considered experimental “off label” and are not FDA-approved. The only exceptions are FDA and Traditional Medicare approved amniotic wound covers for nonhealing diabetic foot ulcers and hyaluronic gel injections for arthritic knees only offered by our affiliate Kentuckiana Medicine not Kentuckiana Integrative Medicine / Kentuckiana Neuro recovery Center. All content, including text and visuals, is for general informational purposes only and is not intended as medical advice. Please consult your medical provider to discuss what’s right for you. Results are variable. No guarantees of successful outcomes are made or implied and individuals should not assume from video testimonials that they will respond favorably.

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Regenerative Medicine for Athletes and Active Adults at Kentuckiana

Regenerative Medicine by Dr. Rafael F. Cruz MD who has practiced medicine for 30+ years and is a physician educator researcher and inventor of Cruz Cric.

Regenerative medicine is transforming recovery for athletes and active individuals eager to return to the activities they love after injury. These innovative treatments can help the body heal itself, even if it has a torn or damaged ACL, meniscus damage, or stubborn tendonitis.

Instead of simply masking pain or relying entirely on surgery, regenerative medicine harnesses the body’s own repair mechanisms.

Two of the most recognized therapies—platelet-rich plasma (PRP) and messenger signaling stem cellular injections—work by delivering concentrated growth factors or healing cells directly to the injury site, aiming to speed recovery and restore function.

The difference at Kentuckiana Regenerative Medicine is experience, thoroughness and advanced techniques. We are one of the few clinics that can harvest messenger signaling stem cellular tissues from abdominal fat and bone marrow. We draw 10x more blood than the average PRP clinic resulting in more PRP. We then enhance the PRP with Vitamins, Procaine and we photo-energize the PRP. In addition, we give all patients IV Vitamin therapy which enhances our results.

Regenerative Medicine Harvested Stem Cell Therapy (explained by Dr. Cruz)

For those who thrive on movement—running, soccer, skiing, or simply staying active—this can be life-changing. Take ACL tears, for example: surgical recovery can stretch over a year, and even then, the knee may never feel quite the same. Early research and patient experiences suggest that PRP and similar treatments may enhance tissue repair beyond what surgery alone can achieve, especially when integrated into a comprehensive rehabilitation plan. For partial tears or post-surgical healing, regenerative techniques are being explored to reduce inflammation, stimulate tissue regeneration, and potentially shorten downtime.

DISCOVER WHAT IS POSSIBLE 60-minute overview

Meniscus injuries are another common setback, particularly for long-time runners or “weekend warriors.” Traditional treatment often involves trimming or removing damaged tissue, which can often increase the risk of arthritis later on. Regenerative therapies aim to preserve more of the joint and encourage natural rebuilding—an appealing option for those hoping to avoid early hip, shoulder or knee replacement.

Then there’s tendinitis- tendonitis—tennis elbow, jumper’s knee, Achilles pain—classic overuse injuries that can linger for months or years. PRP has shown promise in targeting chronic inflammation and promoting new tissue growth in worn-down tendons, offering an alternative to repeated cortisone shots or the frustrating cycle of rest and relapse.

Nancy Purvis – Resumes playing golf

Of course, regenerative medicine isn’t a guaranteed fix. Some patients experience remarkable improvement, while others notice little change. The field is still evolving, and results vary widely.

That’s why consultation with a knowledgeable physician is essential. These treatments aren’t one-size-fits-all—they can be expensive, may not be covered by insurance, and might not be suitable depending on your health, injury severity, or medical history.

If you’re sidelined by injury and seeking a path forward without surgery—or hoping to recover more quickly after one—exploring regenerative options could be worthwhile. Just make sure your decision is guided by accurate information, expert advice, and a clear understanding of the potential benefits and limitations.

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Failed Back Surgery Syndrome? How Regenerative Injections for Pain in Louisville and Kentuckiana Offer New Hope

For those living with chronic back or neck pain, surgery can feel like the ultimate hope—a final solution to reclaim a life free from discomfort. But for some, the reality after the procedure is disheartening. The pain may persist, change, or even worsen, a condition known as Failed Back Surgery Syndrome (FBSS). This condition can be frustrating and isolating experience that can leave you feeling like you’re out of options.

If this is your story, you are not alone. At Kentuckiana Integrative Medicine, we understand this journey. We believe that when surgery does not provide the expected outcome, it’s not the end of the road. In fact, a growing number of people are exploring regenerative injections for pain in Kentuckiana as an advanced and logical next step.

When Surgery Is NOT the Final Answer

The hope of a pain-free future is the most powerful driving force behind placing your trust in a

surgical procedure. When that relief does not happen, the disappointment can be enormous. This experience is somewhat common.  It even has a clinical name, Failed Back Surgery Syndrome (FBSS). That does not mean that the surgery was done incorrectly, or that you have done something wrong during your recovery. That just means that the first mechanical approach did not solve the complicated cause of your pain. This can occur for a number of reasons including scar tissue formation, chronic inflammation or instability in surrounding structures that are now bearing an increased load. Identifying FBSS is the all-important first step to find a different route to recovery.

To learn more, visit our website www.regenmedky.com, email us at kimregenemed@gmail.com and have all your questions answered.  Please call our office at 812-913-4416 to schedule your in-depth consultation $300 paid in advance consultation.

We help patients reverse symptoms of Stroke, TBI, [Perispinal Etanercept] Parkinsons, Heart Disease [Iv chelation, IV phospholipids, Depression, PTSD, CRPS  IV Ketamine Therapy, Erectile Dysfunction, Stress Incontinence, BPH urinary frequency, Cancer Repurposed Medications, IV Vitamin Therapy and IV Hydration, Amniotic Wound care covers for non-healing diabetic foot ulcers and much more.  Discover what is possible at www.regenmedky.com

A New Philosophy: Supporting the Body

A surgical procedure often addresses only one mechanical problem – a herniated disc, a compressed nerve, or an unstable vertebra. While necessary in many cases, it does not always address the widespread inflammation and weakness in the surrounding ligaments, muscles and soft tissues that may also be contributing to the pain.

The regenerative medicine philosophy is different. Instead of removing or fusing structures, regenerative medicine approach focuses on supporting your body’s own powerful, innate ability to repair itself. By using and focusing the healing factors that exist within your own body, the aim is to decrease inflammation, build up weakened tissues and provide a healthier environment where pain can be eliminated.

At our clinic, this is not a 10-minute process. We spend 60 to 120 minutes meticulously and methodically treating the entire spinal area. We believe this all-encompassing approach is essential to attaining a more stable and lasting result.

Real Stories of Hope After Hopelessness

While no specific outcome can be guaranteed, we have seen this supportive approach bring profound changes to many patients’ lives. Their stories are a testament to the potential of regenerative medicine.

Melanie Drury, a Nurse Practitioner suffered nine years of chronic neck and low back pain. She had seen numerous orthopedic surgeons, neurosurgeons and physical therapists before coming to our clinic and had tried all the options available within conventional medicine. After a course of three regenerative injections, she had complete relief from the pain that had troubled her for almost 10 years.

Cindy Moore, who was living with advanced Rheumatoid Arthritis x 30 years and had already had 2 lumbar spine surgeries on her spine with little improvement. Her pain was excruciating and she could only stand for five minutes at a time. She could not shower or dress without extreme pain. After her first regenerative session at our clinic, she proceeded home and cleaned her refrigerator for 90 minutes straight. After completing her recommended series of therapies 1x per week for 3 weeks, she was able to walk two miles without pain and take a Three-week sightseeing trip to Europe with her family – something that was once unthinkable.

Murdayne Nichols avoids Lumbar Spine Fusion

Mark Brooks 52 years old advised that he must have HIP REPLACEMENT surgery.  He proved the surgeons wrong twice.

Nancy Purvis goes from extreme pain getting in and out of her car to golfing 1-2x per week pain free.

Living with persistent pain after back surgery can be a heavy burden, but it does not have to be a life sentence. The goal of regenerative medicine is not to be a magic bullet, but to provide your body with the opportunity to improve. Our commitment is to provide excellent, thorough, and compassionate care.

To find out if regenerative injections for pain in Louisville and Kentuckiana could be the key to improving your quality of life, we invite you to take the next step.  Learn more, visit our website www.regenmedky.com, email us at kimregenemed@gmail.com and have all your questions answered.  Please call our office at 812-913-4416 to schedule your in-depth consultation $300 paid in advance consultation.  Consultation fee is refundable if you invest more than $2,500 in treatment.

We help patients reverse symptoms of Stroke, TBI, [Perispinal Etanercept] Parkinsons, Heart Disease [IV chelation, IV phospholipids, Depression, PTSD, CRPS  IV Ketamine Therapy, Erectile Dysfunction, Stress Incontinence, BPH urinary frequency, Cancer Repurposed Medications, IV Vitamin Therapy and IV Hydration, Amniotic Wound care covers for non-healing diabetic foot ulcers and much more. Discover what is possible at www.regenmedky.com

FDA Disclaimer: All of the therapies offered by Kentuckiana Integrative Medicine / Kentuckiana Neuro Recovery Center are considered experimental “off label” and are not FDA-approved. The only exceptions are FDA and Traditional Medicare approved amniotic wound covers for nonhealing diabetic foot ulcers and hyaluronic gel injections for arthritic knees only offered by our affiliate Kentuckiana Medicine not Kentuckiana Integrative Medicine / Kentuckiana Neuro recovery Center. All content, including text and visuals, is for general informational purposes only and is not intended as medical advice. Please consult your medical provider to discuss what’s right for you. Results are variable. No guarantees of successful outcomes are made or implied and individuals should not assume from video testimonials that they will respond favorably.

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“Bone-on-Bone” Knee Pain? Why Surgery Isn’t Your Only Option

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Kentuckiana Regenerative Medicine has offered Regenerative Medicine therapies for Joint, Spine, Hip, Shoulder And Knee pain in Louisville and Kentuckiana  for over 20 years. We help patients from all over the United States, Canada, and Europe struggling with “Bone-on-Bone” arthritis, Failed Back Surgery Syndrome, Non-Fusing Bones, Joint, Spine, Hip, Shoulder and Knee Pain 

Why Surgery Isn’t Your Only Option

Please watch the numerous unpaid testimonials below to discover all your available options besides surgery. We like to say ‘Discover what is possible”

When you live with severe knee pain or other skeletal pain challenges, chances are that you have heard the term “bone-on-bone.” It is the term that doctors apply to Stage 4 osteoarthritis, a diagnosis that is often accompanied by the grim prognosis of Total Knee Replacement Surgery.

The everyday routine of stabbing pain, the impossibility of doing something simple like walking, gardening, golfing or playing with your grandchildren and so on can make you feel that surgery is the only possible option. You may have been told that you no longer have enough cartilage and that the only way out is to replace the joint.

Are there Regenerative Medicine Injection alternatives that you may not have heard of or considered? What would you think of being able to use the amazing power of your own body to regenerate and self-heal an injured joint or spine, without the risks, long process, cost and uncertainty of a major surgical operation? 

At Kentuckiana Regenerative Medicine, we do not believe surgery should be the first approach to Stage 4 knee arthritis . Surgery should not be a first line defense for many arthritis situations, but rather a last resort. Patients seeking regenerative therapy for spine, joint, hip, shoulder and knee pain in Louisville, as well as those from across the United States and as far away as Canada and Europe, choose our clinic for its proven results. 

Regenerative medicine has provided many of our patients, including those with severe cases of bone-on-bone arthritis, with an avenue of much-needed pain relief and a restoration to the life they love. 

Consultations are $300 paid in advance, but FREE and credited back to you if you invest $2,500+ in your health. We do NOT sell your information and we will NOT call you to schedule an appointment. You will need to call our office to schedule your appointment in person or via Telemedicine Phone/Zoom.

Contact us today on 812-913-4416 or learn more at www.regenmedky.com.

Considering the Full Picture of Knee Replacement Surgery

The replacement of the knee has assisted numerous individuals, and some individuals have no other choice. Joint replacement is a large, invasive operation, and it may have some negative consequences. Although it is generally safe, it may lead to complications such as infection, blood clots, persistent post-surgical pain and sometimes memory disfunction.  Surgery is often expensive with deductibles and time off from work, requires intensive physical therapy often making regenerative therapies a more affordable, practical and effective choice for many individuals since there is minimal down time.

According to medical literature, general anesthesia poses certain risks to older adults. According to one journal, as many as 60 percent of patients older than 60 years of age suffer some type of memory impairment following surgery, and in a minor percentage of instances it may be permanent. These are grave considerations that are worth considering.

And when it comes to making a permanent surgical change to your body, it is worth considering some of the most powerful, least-invasive Regenerative Medicine therapies that can help your body to self-heal.

A New Paradigm: Replacement to Regeneration.

Rather than excising and replacing a damaged joint, regenerative medicine is based on a very simple yet very radical principle of stimulating and assisting your own body to self-heal. Powerful growth factors and signaling cells are present in your body, to repair damage.  We focus these powers and get them to the places where they are most needed.

This therapy does not simply cover up the pain, but rather corrects the root cause, which is to restore and repair the cartilage, ligaments, and soft tissues that are damaged and support the knee, other joints or spine.

Your Arthritis Regenerative Solutions for Severe Arthritis

Dr. Rafael F. Cruz MD has devoted his practice for the past 20 years to the highest level of the most advanced and comprehensive regenerative medicine therapies. The most effective options that we have to offer in the case of severe arthritis are as follows, depending on your particular condition and objectives:

  1. The Gold Standard: Personal Harvested Messenger Signaling “Stem” Cellular Therapy.

It is one of our most advanced options for severe joint degeneration. The process is to harvest your own powerful messenger signaling cells out of your adipose (fat) tissue or bone marrow or use a commercial product. These master cells are then added to our proprietary photo-energized, high volume, hyper-concentrated Platelet-Rich Plasma (PRP), Prolozone and Prolotherapy and carefully injected into the overall structure of the knee- not only the joint space, but also into the ligaments and soft tissues around the joint. This approach offers an entire range of biological materials to decrease inflammation, alleviate pain, and support the regenerative processes of your body. Patients have had continuous benefits in many cases of 5 to 10 years or more. 

Brian Folz was told his meniscus tears are so severe that his only choice is knee surgery. After regenerative Medicine he is in out of his UPS truck doing deliveries and jumps on a trampoline with his children.

Cindy Moore at 61 years old with severe Rheumatoid Arthritis x 30 years became a surgical cripple from 2 lumbar surgeries. She had what is called “Failed Back Surgery Syndrome- FBSS.” With 3 Regenerative Injection Therapy sessions 1x per week, in 4 weeks she was pain free walking 2 miles and ready for her sightseeing trip to Europe.

Joseph Williams dramatically speeds up his knee surgery healing with Regenerative Medicine Therapies.

  1. Hyper-Concentrated Platelet-Rich Plasma (PRP) using your blood

Platelet-Rich Plasma therapy uses the healing ability of your own blood. We take a sample of your blood, and we then subject it to a special procedure to isolate the platelets which are loaded with growth factors that coordinate the process of tissue repair. Our clinic is unique in the sense that it applies multiple techniques to make your PRP more powerful. We photo-energize and  hyper-concentrated your PRP, where 3-12 times more blood is collected than in the normal clinics. This allows for a greater supply of naturally occurring growth factors. The PRP injections can offer relief and better functionality of 6 months to 5+ years.

Mark Brooks 52 years old advised that he must have HIP REPLACEMENT surgery.  He proved the surgeons wrong twice.

Nancy Purvis goes from extreme pain getting in and out of her car to golfing 1-2x per week pain free.

Murdayne Nichols avoids Lumbar Spine Fusion

3. Hyaluronic Gel Injections offer Lubrication and Support:

Hyaluronic Gel injections are an effective and are 100% covered option of knee arthritis to individuals with Traditional Medicare [not Medicare Advantage.] This gel is often referred to as lubricating the joint and is known to cushion and decrease the friction of bone-on-bone contact that can cause a lot of pain and help increase mobility. Some studies even indicate that it may induce some cartilage growth. Hyaluronic Gel injections are 100% covered for knee arthritis by Traditional Medicare with FIVE weekly injections every 6 months. Medicare will not cover other joints at this time. However,  Hyaluronic Gel injections can be used on other joints on a self-pay basis.  

Dr Cruz explains Hyaluronic Gel injections

Hope for “Hopeless” Cases

We understand the skepticism you might feel, especially if you’ve been told your knee is “too far gone.” But we have seen results, even in some of the most advanced cases.

We’ve helped patients like Dr. Chris Rasmussen – 65 years old, who had a knee fracture and a history of meniscus surgery, avoid the operating room.

Boby Dean goes skiing after his Hyaluronic gel injections! 

We’ve helped Rita Jones, an 88-year-old with severe arthritis regain her quality of life.

We’ve helped Mrs. Norcross, a 98-year-old woman with Stage 4 arthritis with a femoral condyle fracture. Her orthopedic surgeon told her she was too old and unhealthy to survive knee replacement surgery. With just 5 weekly hyaluronic gel injections, Mrs. Norcross put away her walker and navigated her 10 basement stairs again to do her favorite activity laundry after just five hyaluronic gel injections. 

Your diagnosis of “bone-on-bone” arthritis does not need to push you into surgery. It can be the beginning of a new journey toward alleviating symptoms and avoiding major surgical procedures. Before you schedule surgery, schedule a consultation to discover if you are a candidate for regenerative medicine.

To learn more, visit our website www.regenmedky.com, email us at kimregenemed@gmail.com and have all your questions answered.  Please call our office at 812-913-4416 to schedule your in-depth consultation $300 paid in advance consultation. Consultation fee is refundable if you invest more than $2,500 in treatment.

Individuals with Traditional Medicare can be seen at NO CHARGE for arthritis knee pain. Medicare currently will not cover any other joints.

We help patients reverse symptoms of Stroke, TBI, [Perispinal Etanercept] Parkinsons, Heart Disease [Iv chelation, IV phospholipids, Depression, PTSD, CRPS  IV Ketamine Therapy, Erectile Dysfunction, Stress Incontinence, BPH urinary frequency, Cancer Repurposed Medications, IV Vitamin Therapy and IV Hydration, Amniotic Wound care covers for non-healing diabetic foot ulcers and much more.  Discover what is possible at www.regenmedky.com

FDA Disclaimer: All the therapies offered by Kentuckiana Integrative Medicine/ Kentuckiana Neuro Recovery Center are considered experimental “off label” and are not FDA-approved. The only exceptions are FDA and Traditional Medicare approved amniotic wound covers for nonhealing diabetic foot ulcers and hyaluronic gel injections for arthritic knees only offered by our affiliate Kentuckiana Medicine not Kentuckiana Integrative Medicine / Kentuckiana Neuro recovery Center. All content, including text and visuals, is for general informational purposes only and is not intended as medical advice. Please consult your medical provider to discuss what’s right for you. Results are variable. No guarantees of successful outcomes are made or implied and individuals should not assume from video testimonials that they will respond favorably.

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About Us

405 E Court Ave #102, Jeffersonville, IN 47130
(812) 913-4416

We are located across Louisville, KY, in Jeffersonville, IN, and welcoming new patients of all ages

DISCLAIMER NOTICE: We make NO claims that ANY of our supportive therapies can cure or heal any disease process. Our treatments and therapies can provide symptom relief and support your bodies self-healing mechanisms. Only FDA approved therapies can be declared curative of disease. All information including video testimonials are purely educational and no implied or direct claims of a patient experiencing a benefit are made. Results CANNOT be guaranteed and vary based on multiple variables especially patient’s level of health and receptiveness. Only GOD, you and FDA therapies can cure you of a disease. Additionally, educational information regarding many of the services and or commercial products discussed are NOT offered. Our focus is on Injections of Prolozone, Prolotherapy, Platelet Rich Plasma, Harvested Adipose “Fat” and Bone Marrow Messenger Signaling Cells all collected administered as within same day procedure FDA guidelines with minimal manipulation [no enzymes are used.] 

Regarding Stem Cell Injection Therapy and Regenerative Medicine Pain Relief Injections, we are one of the most experienced clinics in the USA. Our most experienced physician has been providing these services since 2010 which were the early days of Platelet Rich Plasma and Stem Cell Therapy. We are extremely experienced in the use of ultrasound and fluoroscopy guided injections offering precision needle placement when needed. We focus on FDA approved procedures and products [especially wound care that are even approved by some insurances] and FDA approved and permitted “same day procedures” that include but are not limited to Collecting [Harvesting] a patient’s Adipose “Belly Fat” Messenger Signaling Cells and Bone Marrow Messenger Signaling Cells, Platelet Rich Plasma Injections [from your blood], Prolozone and Prolotherapy. Collection of “fat” messenger signaling cells and bone marrow messenger signaling cells can be done very comfortably and with very little or no pain with proper numbing techniques. Currently, the FDA allows the above “same day procedures” or injection therapies under FDA rule 21 CFR 1271.15.  The FDA has approved a very few injectable commercial regenerative products under FDA rule 21 CFR 1271.10 mostly wound care products for homologous use with skin problems such as burns and wounds.

FDA DISCLAIMER: Our treatments are considered “off-label,” meaning they are not FDA approved to diagnose, treat, cure, or prevent any disease or condition. Individual results will vary depending on each patient’s overall health and mindset, and no outcomes are guaranteed. These therapies are intended to support the body’s natural healing response and may help improve function and quality of life. Testimonials reflect individual experiences and do not imply or guarantee that you will experience similar results.

© Kentuckiana Integrative Medicine (Louisville) 2026
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