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Stroke, TBI and Nerve Damage Treatments in Jeffersonville, IN

At Kentuckiana Integrative Medicine, we offer a unique, physician-led treatment that targets the brain through a specialized pathway in the neck, making the process safer and more precise. This expert technique is exclusively performed by Dr. Rafael F. Cruz, MD, who brings over 30 years of experience in emergency medicine, anesthesiology, and integrative care. The complete treatment takes about a week, but many patients report noticeable improvements in as little as two hours after the first session. Because of its effectiveness and rarity, we see patients traveling from all 50 states, Europe, and beyond to receive this advanced therapy.

DISCLAIMER NOTICE: We make NO claims that ANY of our supportive therapies can cure or heal any disease process. Our treatments and therapies can provide symptom relief and support your bodies self-healing mechanisms. Only FDA approved therapies can be declared curative of disease. All information including video testimonials are purely educational and no implied or direct claims of a patient experiencing a benefit are made. Results CANNOT be guaranteed and vary based on multiple variables especially patient’s level of health and receptiveness. Only GOD, you and FDA therapies can cure you of a disease. Additionally, educational information regarding many of the services and or commercial products discussed are NOT offered. Our focus is on Injections of Prolozone, Prolotherapy, Platelet Rich Plasma, Harvested Adipose “Fat” and Bone Marrow Messenger Signaling Cells all collected administered as within same day procedure FDA guidelines with minimal manipulation [no enzymes are used.] 

Regarding Stem Cell Injection Therapy and Regenerative Medicine Pain Relief Injections, we are one of the most experienced clinics in the USA. Our most experienced physician has been providing these services since 2010 which were the early days of Platelet Rich Plasma and Stem Cell Therapy. We are extremely experienced in the use of ultrasound and fluoroscopy guided injections offering precision needle placement when needed. We focus on FDA approved procedures and products [especially wound care that are even approved by some insurances] and FDA approved and permitted “same day procedures” that include but are not limited to Collecting [Harvesting] a patient’s Adipose “Belly Fat” Messenger Signaling Cells and Bone Marrow Messenger Signaling Cells, Platelet Rich Plasma Injections [from your blood], Prolozone and Prolotherapy. Collection of “fat” messenger signaling cells and bone marrow messenger signaling cells can be done very comfortably and with very little or no pain with proper numbing techniques. Currently, the FDA allows the above “same day procedures” or injection therapies under FDA rule 21 CFR 1271.15.  The FDA has approved a very few injectable commercial regenerative products under FDA rule 21 CFR 1271.10 mostly wound care products for homologous use with skin problems such as burns and wounds.

Cardiovascular Issues

Heart Disease, Poor Blood Flow, Other Issues

Neurological Issues

Stroke, TBI, MS,
SCI, Parkinsons

Mental Health

Depression, PTSD, Anxiety, ADD, MS, Addictions

Regenerative Medicine

Personal Messenger Signaling Cell Therapy

Neuropathy Treatment

Neuropathy Pain Therapy, Pain, Numbness

Dr. Cruz of Kentuckiana Integrative Medicine

Dr. Rafael F. Cruz, MD

Dr. Rafael F. Cruz, MD is a nationally recognized expert in Integrative Medicine, combining conventional medical practices with holistic, natural therapies. As the founder of Kentuckiana Integrative Medicine, he offers advanced, patient-centered treatments that target the root causes of complex health issues. With over 30 years of clinical experience, Dr. Cruz collaborates closely with patients and their primary doctors to deliver personalized care that promotes long-term healing.

His credentials include board certification in Emergency Medicine (1997–2017), advanced training in ultrasound- and fluoroscopic-guided injections, regenerative therapies (including PRP, prolotherapy, and signaling cell treatments), and certifications in IV Chelation, Plaquex, and nutritional therapy.

At Kentuckiana Integrative Medicine, we treat the whole person—not just your symptoms. Our approach focuses on identifying and addressing the root causes of illness to promote long-term healing and vitality. By blending the best of conventional and alternative medicine, our experienced team helps patients restore energy, strength, and overall well-being. We understand that the body has remarkable self-healing capabilities, which can be diminished by age, stress, lifestyle, or environmental factors. That’s why we use advanced integrative and functional therapies to give your body the tools it needs to recover and thrive.

Located just five minutes from Louisville, KY, Kentuckiana Integrative Medicine is a regional leader in innovative, non-surgical treatments. Our clinic offers regenerative solutions such as platelet-rich plasma (PRP), personal messenger signaling cell therapy, prolozone, and hormone optimization. Whether you’re dealing with chronic pain, fatigue, hormone imbalance, or complex medical issues, our doctors draw on more than 100 years of combined clinical experience to create personalized treatment plans that deliver real results.

We go beyond symptom management to support your body’s natural ability to heal and rebuild. From your initial consultation through every step of your care, our focus is helping you feel better, function better, and live with renewed energy. If traditional medicine hasn’t provided the answers you need, Kentuckiana Integrative Medicine offers an experienced, compassionate, and results-driven alternative. Discover how our whole-person approach can help you reclaim your health and get back to living fully.