KETAMINE THERAPY & MENTAL HEALTH
Depression · PTSD · OCD · Anxiety · Suicidal Ideation · CRPS Pain
The Kentuckiana Ketamine Institute: 10+ Years. First in the Region. Zero Serious Adverse Events.
Kentuckiana Integrative Medicine was among the first practices in the Louisville/Southern Indiana region to offer medical ketamine therapy for treatment-resistant mental health conditions. Dr. Cruz has over 25 years of ketamine administration experience from his anesthesia and emergency medicine background — and has personally administered ketamine to every mental health patient in our clinic. We have never had a serious adverse event.
Ketamine’s effect on treatment-resistant depression has been called one of the most significant discoveries in psychiatry in 50 years. Unlike standard antidepressants requiring 4–8 weeks (and often failing), IV ketamine may produce measurable improvement in mood and suicidal ideation within hours to days.
Conditions Supported
Mental Health
- Major Depressive Disorder (MDD)
- Treatment-Resistant Depression
- Bipolar Depression
- Post-Traumatic Stress Disorder (PTSD)
- OCD — Obsessive-Compulsive Disorder
- Postpartum Depression
- Suicidal Ideation — Crisis Intervention
- Generalized & Social Anxiety
Pain Conditions
- Complex Regional Pain Syndrome (CRPS)
- Fibromyalgia
- Neuropathic Pain
- Chronic Migraines
- Central Sensitization Syndromes
- Opioid Reduction Support
- Addiction (combined with NAD+ therapy)
- Long COVID Neurological Symptoms
Our 5R Ketamine Protocol — Why Our Outcomes Exceed Standard Ketamine Clinics
Standard ketamine clinics give ketamine alone. Our proprietary 5R protocol layers ketamine with complementary IV and oral therapies — IV amino acids, IV NAD+, IV magnesium, targeted nutrition — to support the neuroplasticity window ketamine opens, address underlying nutritional deficiencies, and extend the duration of benefit. More comprehensive = better results.
80–90%
Patient response rate with our 5R Protocol (significant symptom reduction)
65–75%
Response rate with standard ketamine protocols alone
36%
Response rate from a single antidepressant medication (published literature average)
25+ yrs
Dr. Cruz’s personal ketamine administration experience — zero serious adverse events
Get Back to Feeling Good!
Our treatment approaches transform lives from dysfunctional to functional.
SERVICE
INVESTMENT
Basic Ketamine Package (7 treatments)
$2,500
Enhanced 5R Protocol
$2,500 – $6,000
CRPS Intensive Protocol
$5,000
Suicidal Ideation / Crisis Intervention
Call for urgent scheduling
REGULATORY NOTICE
Ketamine is FDA-approved ONLY as an anesthetic. Its use for depression, PTSD, anxiety, OCD, pain, and other mental health conditions is off-label and investigational. IV ketamine for mental health is not covered by insurance. Individual responses vary significantly. 5R protocol response rates are based on clinical observation and published ketamine literature ranges — they are not guaranteed outcomes and have not been evaluated in FDA-approved trials for this specific protocol.
What Patients Say
Chronically Depressed Patient Finds Relief with Ketamine Therapy